Functional characterization of the alanine-serine-cysteine exchanger of Carnobacterium sp AT7

P Bartoccioni, J Fort, A Zorzano… - Journal of General …, 2019 - rupress.org
Many key cell processes require prior cell uptake of amino acids from the environment,
which is facilitated by cell membrane amino acid transporters such as those of the L-type …

Identification of amino acid residues underlying the antiport mechanism of the mitochondrial carnitine/acylcarnitine carrier by site-directed mutagenesis and chemical …

N Giangregorio, L Console, A Tonazzi, F Palmieri… - Biochemistry, 2014 - ACS Publications
The mitochondrial carnitine/acylcarnitine carrier catalyzes the transport of carnitine and
acylcarnitines by antiport as well as by uniport with a rate slower than the rate of antiport …

Structural insights into the elevator-like mechanism of the sodium/citrate symporter CitS

JW Kim, S Kim, S Kim, H Lee, JO Lee, MS Jin - Scientific reports, 2017 - nature.com
The sodium-dependent citrate transporter of Klebsiella pneumoniae (Kp CitS) belongs to the
2-hydroxycarboxylate transporter (2-HCT) family and allows the cell to use citrate as sole …

[HTML][HTML] Substrate discrimination by ergothioneine transporter SLC22A4 and carnitine transporter SLC22A5: gain-of-function by interchange of selected amino acids

P Bacher, S Giersiefer, M Bach, C Fork… - … et Biophysica Acta (BBA …, 2009 - Elsevier
ETT (originally designated as OCTN1; human gene symbol SLC22A4) and CTT (OCTN2;
SLC22A5) are highly specific transporters of ergothioneine and carnitine, respectively …

Structure and function of polyamine-amino acid antiporters CadB and PotE in Escherichia coli

H Tomitori, K Kashiwagi, K Igarashi - Amino acids, 2012 - Springer
The structure and function of a cadaverine–lysine antiporter CadB and a putrescine–
ornithine antiporter PotE in Escherichia coli were evaluated using model structures based …

Crystal structure of the bacterial acetate transporter SatP reveals that it forms a hexameric channel

P Sun, J Li, X Zhang, Z Guan, Q Xiao, C Zhao… - Journal of Biological …, 2018 - ASBMB
Acetate is found ubiquitously in the natural environment and can be used as an exogenous
carbon source by bacteria, fungi, and mammalian cells. A representative member of the …

The mitochondrial carnitine acyl-carnitine carrier (SLC25A20): molecular mechanisms of transport, role in redox sensing and interaction with drugs

A Tonazzi, N Giangregorio, L Console, F Palmieri… - Biomolecules, 2021 - mdpi.com
The SLC25A20 transporter, also known as carnitine acyl-carnitine carrier (CAC), catalyzes
the transport of short, medium and long carbon chain acyl-carnitines across the …

[引用][C] On sialic acid transport and utilization by Vibrio cholerae

GH Thomas, EF Boyd - Microbiology, 2011 - microbiologyresearch.org
The scavenging of host-derived sialic acid is important for a number of human pathogens
during colonization of mammalian mucous membranes (Severi et al., 2007). This has been …

Cysteine 467 of the ASCT2 amino acid transporter is a molecular determinant of the antiport mechanism

M Scalise, G Pappacoda, T Mazza, L Console… - International Journal of …, 2022 - mdpi.com
The plasma membrane transporter ASCT2 is a well-known Na+-dependent obligatory
antiporter of neutral amino acids. The crucial role of the residue C467 in the recognition and …

The making of a potent L-lactate transport inhibitor

PD Bosshart, D Kalbermatter, S Bonetti… - Communications …, 2021 - nature.com
L-lactate is an important metabolite, energy source, and signaling molecule in health and
disease. In mammals, its transport across biological membranes is mediated by …