Patients with neuromuscular disease risk developing chest infections due to the inability to
cough effectively and to maintain adequate lung volume. This systematic review aimed to …

12 In 1852, the English physician MERYON [1] described how a 16-yr-old male with what
was to become known as Duchenne muscular dystrophy, died from acute respiratory failure …

Background Respiratory muscle weakness can impair cough function, leading to lower
respiratory tract infections. These infections are an important contributor to morbidity and …

BACKGROUND It has been suggested that cough effectiveness can be improved by
assisted techniques. The effects of manually assisted cough and mechanical insufflation on …

We read with interest the work by Andersen et al1 about transnasal laryngoscopy during
mechanical insufflation-exsufflation in amyotrophic lateral sclerosis (ALS). We believe the …

Bronchial mucous plugging is the main precipitating factor of acute respiratory failure for
patients with neuromuscular disease. Manually assisted coughing and mechanical …

Elimination of airway secretion is a major issue in the care of patients with ALS. Sufficient
cough flows have to be generated by expiratory muscles to allow airway clearance. Bulbar …

Introduction Patients with neuromuscular disease often have a weak and ineffective cough
due to respiratory muscle weakness. One treatment option is mechanical insufflation …

Purpose To assess the ability of a mechanical in-exsufflator (MI-E), either alone or in
combination with manual thrust, to augment cough in patients with neuromuscular disease …

Pulmonary complications are major causes of morbidity and mortality for patients with
severe expiratory muscle weakness. The purpose of this study was to compare peak cough …