Misoprostol for the prevention and treatment of postpartum haemorrhage

GJ Hofmeyr, AM Gülmezoglu - Best Practice & Research Clinical Obstetrics …, 2008 - Elsevier
Postpartum haemorrhage (PPH) causes preventable maternal deaths, mainly in low-income
countries. Misoprostol has powerful uterotonic effects and, because it is well absorbed orally …

Misoprostol for the prevention and treatment of postpartum hemorrhage

WR Sheldon, J Blum, J Durocher… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Uterotonic drugs are recommended for the prevention and treatment of
postpartum hemorrhage (PPH), and oxytocin is considered the gold standard for both …

Misoprostol for treating postpartum haemorrhage: a randomized controlled trial [ISRCTN72263357]

GJ Hofmeyr, S Ferreira, VC Nikodem… - BMC pregnancy and …, 2004 - Springer
Background Postpartum haemorrhage remains an important cause of maternal death
despite treatment with conventional therapy. Uncontrolled studies and one randomised …

Prevention of postpartum hemorrhage with misoprostol

Z Alfirevic, J Blum, G Walraven, A Weeks… - International Journal of …, 2007 - Elsevier
As a stable, orally active and cheap uterotonic, misoprostol would appear ideally suited to
the prevention of postpartum hemorrhage (PPH) in the developing world. Following …

[PDF][PDF] Misoprostol to prevent and treat postpartum haemorrhage: a systematic review and meta-analysis of maternal deaths and dose-related effects

GJ Hofmeyr, AM Gülmezoglu… - Bulletin of the World …, 2009 - SciELO Public Health
OBJECTIVE: To review maternal deaths and the dose-related effects of misoprostol on blood
loss and pyrexia in randomized trials of misoprostol use for the prevention or treatment of …

Misoprostol for prevention and treatment of postpartum haemorrhage: a systematic review

KM Olefile, O Khondowe, D M'Rithaa - curationis, 2013 - journals.co.za
Background: Postpartum haemorrhage (PPH) is a leading cause of maternal mortality
especially in the developing world. Misoprostol, a highly effective drug is highly effective in …

Misoprostol for prevention and treatment of postpartum hemorrhage: What do we know? What is next?

S Raghavan, D Abbas, B Winikoff - International Journal of …, 2012 - Wiley Online Library
Misoprostol is an effective and safe uterotonic for the prevention and treatment of postpartum
hemorrhage (PPH). A 600‐μg oral dose of misoprostol has been shown to prevent PPH in …

Use of oral misoprostol in the prevention of postpartum haemorrhage

H El‐Refaey, P O'Brien, W Morafa… - … Journal of Obstetrics …, 1997 - Wiley Online Library
Objective To investigate the use of the oral prostaglandin E1 analogue, misoprostol in the
prevention of postpartum haemorrhage. Design A prospective observational study. Setting A …

Misoprostol in preventing postpartum hemorrhage: A meta-analysis

C Langenbach - International Journal of Gynecology & Obstetrics, 2006 - Elsevier
Objective: To assess misoprostol's ability to prevent postpartum hemorrhage (PPH) where
no alternatives exist. Comparison to oxytocics demonstrates how similarly misoprostol …

Misoprostol in the treatment of postpartum haemorrhage in addition to routine management: a placebo randomised controlled trial

G Walraven, Y Dampha, B Bittaye… - … Journal of Obstetrics …, 2004 - Wiley Online Library
Postpartum haemorrhage remains a leading cause of maternal mortality, despite treatment
with conventional methods. In this randomised controlled trial, we compared misoprostol …