Exposure to fluoride exacerbates the cognitive deficit of diabetic patients living in areas with endemic fluorosis, as well as of rats with type 2 diabetes induced by …

J Xiang, XL Qi, K Cao, LY Ran, XX Zeng, X Xiao… - Science of The Total …, 2024 - Elsevier
Epidemiology has shown that fluoride exposure is associated with the occurrence of
diabetes. However, whether fluoride affects diabetic encephalopathy is unclear. Elderly …

Fluoride exposure impairs glucose tolerance via decreased insulin expression and oxidative stress

EA García-Montalvo, H Reyes-Pérez, LM Del Razo - Toxicology, 2009 - Elsevier
Chronic exposure to high fluoride (F−) may lead to local tissue disturbances, known as
fluorosis. F− is an oxidising agent and a well-known reversible enzymatic inhibitor that …

In vivo measurement of fluoride effects on glucose homeostasis: an explanation for the decrease in intelligence quotient and insulin resistance induced by fluoride

M Lombarte, BL Fina, PM Lupión, M Lupo, A Rigalli - 2016 - ri.conicet.gov.ar
The fluoride ion (F) is a disturbing substance for the glucose-insulinsystem. The effects of F
have been studied in various aspects. The chronic intake ofF generates hyperglycaemia …

Low-level fluoride exposure increases insulin sensitivity in experimental diabetes

J Lobo, AL Leite, H Pereira… - Journal of Dental …, 2015 - journals.sagepub.com
The effect of chronic fluoride (F) exposure from the drinking water on parameters related to
glucose homeostasis was investigated. Wistar rats were randomly distributed into 2 groups …

[HTML][HTML] Effects of low-level fluoride exposure on glucose homeostasis in female NOD mice

JS Trevizol, NR Buzalaf, A Dionizio, AQ Delgado… - Chemosphere, 2020 - Elsevier
Water fluoridation is an important public health measure for the control of dental caries.
Recent animal studies have shown that low doses of fluoride (F) in the drinking water …

Low glucose utilization and neurodegenerative changes caused by sodium fluoride exposure in rat's developmental brain

C Jiang, S Zhang, H Liu, Z Guan, Q Zeng… - Neuromolecular …, 2014 - Springer
Fluorine, a toxic and reactive element, is widely prevalent throughout the environment and
can induce toxicity when absorbed into the body. This study was to explore the possible …

Low-level fluoride exposure reduces glycemia in NOD mice

MAPN Malvezzi, HABS Pereira, A Dionizio… - Ecotoxicology and …, 2019 - Elsevier
Water fluoridation is the most widespread measure to prevent dental caries but its
relationship with the development of type-1 diabetes (T1D), which has been increasing by 2 …

Absence of detrimental effects of fluoride exposure in diabetic rats

AJ Dunipace, CA Wilson, ME Wilson, W Zhang… - Archives of oral …, 1996 - Elsevier
This study is part of a comprehensive programme to investigate fluoride toxicity and the
hypothesis that fluoride ingested by 'medically compromised'animals will result in altered …

[HTML][HTML] Metabolic effect of low fluoride levels in the islets of NOD mice: integrative morphological, immunohistochemical, and proteomic analyses

JS Trevizol, A Dionizio, AQ Delgado… - Journal of Applied Oral …, 2023 - SciELO Brasil
Fluoride (F) has been widely used to control dental caries, and studies suggest beneficial
effects against diabetes when a low dose of F is added to the drinking water (10 mgF/L) …

The effects of fluoride on inflammation and cancer

B Spittle - Fluoride, 2019 - search.proquest.com
Two papers in the current issue of Fluoride report that (i) the insulin resistance induced by
excessive fluoride intake in rats may be mediated by activation of inflammatory signaling …