The use of fluoridated products has significantly contributed to the reduction in rates of
dental caries. However, excessive sodium fluoride (NaF) intake promotes inhibition of …

Fluorosis can induce neurotoxicity. Sodium butyrate (SB), a histone deacetylase inhibitor,
has important research potential in correcting glucose metabolism disorders and is widely …

Background Potential protection against the neurotoxic damages of high levels of fluoride on
rats and SH-SY5Y cells by extract of Ginkgo biloba leaves, as well as underlying …

To explore the mechanisms by which chronic fluorosis damages the brain, we determined
the levels of the advanced glycation end-products (AGEs), the receptor for AGE (RAGE) …

Although the literature does not provide evidence of health risks from exposure to fluoride
(F) in therapeutic doses, questions remain about the effects of long-term and high-dose use …

This investigation was designed to examine the potential involvement of RAGE/NADPH
oxidase signaling in the damage to the brain caused by chronic fluorosis. Sprague-Dawley …

Diabetic cognitive dysfunction is common in patients with diabetes but its pathogenesis is
not clear. The aim of the present study is to investigate the role of 5', 10'methylene …

Perfluoro–alkyl substances (PFAS) are chemical pollutants with prevalent stability and
environmental persistence. Exposure to PFAS, particularly perfluoro-octanoic acid (PFOA) …

Fluorosis is a global public health concern. Prolonged exposure to excessive fluoride
causes fluoride accumulation in the hippocampus, resulting in cognitive dysfunction. Cell …

Background: Exposure to per-and polyfluoroalkyl substances (PFAS), a prevalent class of
persistent pollutants, may increase the risk of type 2 diabetes. Objective: We examined …