miR‐124 interacts with the Notch1 signalling pathway and has therapeutic potential against gastric cancer

L Jiang, T Lin, C Xu, S Hu, Y Pan… - Journal of cellular and …, 2016 - Wiley Online Library
Aberrant Notch signalling plays an important role in cancer progression. However, little is
known about the interaction between mi RNA and the Notch signalling pathway and its role …

miR-935 suppresses gastric signet ring cell carcinoma tumorigenesis by targeting Notch1 expression

C Yan, J Yu, W Kang, Y Liu, Z Ma, L Zhou - Biochemical and biophysical …, 2016 - Elsevier
Gastric signet ring cell carcinoma (GSRCC) is a unique pathological type of gastric
carcinoma that is extremely invasive and has a poor prognosis. Expression of microRNAs …

[HTML][HTML] Tumor-Suppressive MicroRNA-708 Targets Notch1 to Suppress Cell Proliferation and Invasion in Gastric Cancer

X Li, X Zhong, X Pan, Y Ji - Oncology research, 2018 - ncbi.nlm.nih.gov
Growing evidence has demonstrated that numerous microRNAs (miRNAs) may participate
in the regulation of gastric carcinogenesis and progression. This phenomenon suggests that …

[HTML][HTML] Notch1 pathway-mediated microRNA-151-5p promotes gastric cancer progression

KW Hsu, WL Fang, KH Huang, TT Huang, HC Lee… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Gastric carcinoma is the third leading cause of lethal cancer worldwide. Previous studies
showed that Notch1 receptor intracellular domain (N1IC), the activated form of Notch1 …

[HTML][HTML] The reciprocal regulation loop of Notch2 pathway and miR-23b in controlling gastric carcinogenesis

TT Huang, YH Ping, AM Wang, CC Ke, WL Fang… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Gastric carcinoma is one of the most common malignancies and the third highest cause of
global cancer-related death. Notch2 receptor intracellular domain (N2IC), the activated form …

NOTCH3, a crucial target of miR-491-5p/miR-875-5p, promotes gastric carcinogenesis by upregulating PHLDB2 expression and activating Akt pathway

W Kang, J Zhang, T Huang, Y Zhou, CC Wong… - Oncogene, 2021 - nature.com
Aberrant Notch activation has been implicated in multiple malignancies and the
identification of NOTCH receptors and related pathways is critical for targeted therapy. In this …

Retracted: In vivo and in vitro effects of microRNA‐124 on human gastric cancer by targeting JAG1 through the Notch signaling pathway

HJ Xiao, Q Ji, L Yang, RT Li, C Zhang, JM Hou - 2018 - Wiley Online Library
In this study, we aim to determine the function of miR‐124 on gastric cancer (GC) cells and
the underlying mechanism that involves jaddeg1 (JAG1) and the Notch signaling pathway …

MicroRNA-140-5p inhibits cell proliferation, migration and promotes cell apoptosis in gastric cancer through the negative regulation of THY1-mediated Notch signaling

K Wu, J Zou, C Lin, ZG Jie - Bioscience reports, 2019 - portlandpress.com
Studies have highlighted the importance of microRNAs (miRs) in the development of various
cancers, including gastric cancer (GC), a commonly occurring malignancy, accompanied by …

[HTML][HTML] MiR-92 suppresses proliferation and induces apoptosis by targeting EP4/Notch1 axis in gastric cancer

VY Shin, MT Siu, X Liu, EKO Ng, A Kwong, KM Chu - Oncotarget, 2018 - ncbi.nlm.nih.gov
MiR-92a has been shown to be dysregulated in various cancers and exhibited differential
role in carcinogenesis. In this study, we sought to delineate the functional role of miR-92a …

miR‐449c‐5p availability is antagonized by circ‐NOTCH1 for MYC‐induced NOTCH1 upregulation as well as tumor metastasis and stemness in gastric cancer

X Zhao, Q Zhong, X Cheng, S Wang… - Journal of Cellular …, 2020 - Wiley Online Library
Gastric cancer (GC), identified as the most common gastrointestinal malignancy, is one of
the primary causes of cancer‐related mortality in the world. Although surgery and …