Patients with psychiatric disorders, such as gambling and substance use, tend to exhibit
maladaptive decision-making. In this study, we assessed individual differences in risk-taking …

Background Excessive risk taking is a characteristic trait of several psychiatric conditions,
including substance use disorders. High risk-taking (HiR) rats self-administer more cocaine …

Poor decision-making is a core problem in psychiatric disorders such as pathological
gambling and substance abuse. Both trait and environmental factors are considerably …

Methamphetamine withdrawal can induce intense cravings leading to relapse.
Contexts/cues paired with chronic methamphetamine use develop incentive motivational …

Rationale Decision-making deficits, measured using the Iowa Gambling Task (IGT), are
observed in many psychiatric populations. Additionally, evidence suggests that the …

Accrued evidence demonstrated the necessity of protein synthesis at acquisition,
consolidation and expression stages in conditioning/learning tasks, while the underlying …

Rationale It has been demonstrated that major differences between mice of the C57BL/6J
and DBA/2J inbred strains for amphetamine-induced place conditioning (preference and …

Drug memory plays an important role in priming subsequent drug use. We used drug-
induced conditioned place preference (CPP) as a paradigm to study such drug memory. In …

The studies for the effects of stress on drug addiction were mostly obtained using sequential
exposure to stress and drugs. However, few studies have been conducted on the effects of …

The effect of exposure of male mice to a horizontal running wheel (Fast-Trac™) on
conditioned place preference (CPP) and hyperlocomotion induced by methamphetamine …