Circuits in the cerebral cortex consist of thousands of neurons connected by millions of
synapses. A precise understanding of these local networks requires relating circuit activity …

In the cerebral cortex, local circuits consist of tens of thousands of neurons, each of which
makes thousands of synaptic connections. Perhaps the biggest impediment to …

The specificity of cortical neuron connections creates columns of functionally similar neurons
spanning from the pia to the white matter,,,,,. Here we investigate whether there is an …

Sensory processing occurs in neocortical microcircuits in which synaptic connectivity is
highly structured,,, and excitatory neurons form subnetworks that process related sensory …

The strength of synaptic connections fundamentally determines how neurons influence each
other's firing. Excitatory connection amplitudes between pairs of cortical neurons vary over …

How a sensory stimulus is processed and perceived depends on the surrounding sensory
scene. In the visual cortex, contextual signals can be conveyed by an extensive network of …

Neuronal connectivity is fundamental to information processing in the brain. Therefore,
understanding the mechanisms of sensory processing requires uncovering how connection …

The selectivity of neuronal responses arises from the architecture of excitatory and inhibitory
connections. In the primary visual cortex, the selectivity of a neuron in layer 2/3 for stimulus …

In this Historical Perspective, we ask what information is needed beyond connectivity
diagrams to understand the function of nervous systems. Informed by invertebrate circuits …

Here we ask whether visual response pattern varies with position in the cortical microcircuit
by comparing the structure of receptive fields recorded from the different layers of the cat's …