DNA methylation on cytosine in vertebrates such as zebrafish serves to silence gene
expression by interfering with the binding of certain transcription factors and through the …

Genomic DNA methylation functions to repress gene expression by interfering with
transcription factor binding and/or recruiting repressive chromatin machinery. Recent data …

DNA methylation is an epigenetic mark associated with transcriptional repression and
essential for proper vertebrate development. Because of its association with human …

DNA methylation is crucial for normal development and cellular differentiation in many large-
genome eukaryotes. The small tropical freshwater fish Danio rerio (zebrafish) has recently …

DNA methylation reprogramming, the erasure of DNA methylation patterns shortly after
fertilization and their reestablishment during subsequent early development, is essential for …

The DNA methylation landscape is dynamically patterned during development and distinct
methylation patterns distinguish healthy from diseased cells. However, whether tissue …

Methylation of cytosines in the CG context (mCG) is the most abundant DNA modification in
vertebrates that plays crucial roles in cellular differentiation and identity. After fertilization …

DNA methylation is a dynamic process through which specific chromatin modifications can
be stably transmitted from parent to daughter cells. A large body of work has suggested that …

We have examined the methylation status of the zebrafish genome during early
embryogenesis and we find evidence that methylation fluxes do occur in that organism. The …

DNA methylation is an important epigenetic modification that has been repeatedly implied in
organismal adaptation. However, many previous studies that have linked DNA methylation …