Although clinical outcomes for patients with rheumatoid arthritis (RA) have greatly improved
with the use of biologic and conventional DMARDs, approximately 40% of patients do not …

Lymphatic vessel networks are a main part of the vertebrate cardiovascular system, which
participate in various physiological and pathological processes via regulation of fluid …

Proliferation of draining lymphatic vessels coupled with dynamic changes in lymph node
volume and flow are characteristic features in rheumatoid arthritis (RA). Furthermore …

Background Osteoarthritis (OA) affects the entire joint, initially with a low degree of
inflammation. Synovitis is correlated with the severity of OA clinical symptoms and cartilage …

Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease of unknown
aetiology, leading to progressive damage of bone and cartilage with functional impairment …

Lymphatic vessels are critical for clearing fluid and inflammatory cells from inflamed tissues
and also have roles in immune tolerance. Given the functional association of the lymphatics …

Rheumatoid arthritis (RA) is a prevalent inflammatory joint disease with enigmatic flares,
which causes swelling, pain, and irreversible connective tissue damage. Recently, it has …

Objective This study was undertaken to investigate the effect of lymphatic inhibition on joint
and draining lymph node (LN) pathology during the course of arthritis progression in mice …

Key points Previously, it was found that the popliteal lymph node (PLN) enlarges during the
pre‐arthritic 'expanding'phase, and then 'collapses' with adjacent knee flare and is …

The lymphatic vasculature plays a crucial role in regulating the inflammatory response by
influencing drainage of extravasated fluid, inflammatory mediators, and leukocytes …