Inorganic phosphate (Pi) is required by all living organisms for the development of organs
such as bone, muscle, brain, and lungs, regulating the expression of several critical genes …

Rationale: Phosphate (Pi) is an essential nutrient to living organisms. Recent surveys
indicate that the intake of Pi has increased steadily. Our previous studies have indicated that …

Recent surveys indicate that Pi intake has increased steadily as Pi-containing foods have
increased. Our previous study demonstrated that high dietary Pi strongly stimulated lung …

In this article, we briefly summarized evidence that cellular phosphate burden from
phosphate toxicity is a pathophysiological determinant of cancer cell growth. Tumor cells …

Background Altered cell metabolism is regarded as a hallmark of cancer with numerous
studies highlighting glucose and glutamine as critical nutrients for tumor proliferation …

Inorganic phosphate (Pi) plays a key role in diverse physiological functions. Several studies
indicate that Pi may affect lung cell development through Na/Pi cotransporter (NPT). Several …

Phosphorus, often in the form of inorganic phosphate (Pi), is critical to cellular function on
many levels; it is required as an integral component of kinase signaling, in the formation and …

Tumor epidemiology, as well as tumor microenvironments and cancer cell signaling study,
has been presented with statistical relevance of inorganic phosphate (Pi) to tumorigenesis …

The present perspective article proposes that cachexia, muscle wasting in cancer, is
mediated by dysregulated phosphate metabolism and phosphate toxicity that can damage …

Inorganic phosphate (Pi) is an essential nutrient for human health. Due to the changes in our
dietary pattern, dietary Pi overload engenders systemic phosphotoxicity, including excessive …