Targeted therapy moves to earlier stages of non-small-cell lung cancer: emerging evidence, controversies and future challenges

X Mielgo-Rubio, M Martín, J Remon, O Higuera… - Future …, 2021 - Future Medicine
Lung cancer continues to be the leading cause of cancer mortality and a serious health
problem despite the numerous advances made in the last decade and the rapid advance of …

The evolving role of targeted therapy in early-stage and locally advanced non-small cell lung cancer

H West - Current oncology reports, 2011 - Springer
Many of the leading developments in management of non-small cell lung cancer (NSCLC)
have been provided by the integration of specific targeted therapies either in combination …

Targeted therapy for lung cancer: present and future

C Aggarwal - Annals of palliative medicine, 2014 - apm.amegroups.org
Recent advances in methods of genomic profiling have accelerated our understanding of
the biology of oncologic diseases. Accumulating evidence suggests that both histology and …

Targeted therapies and non-small-cell lung cancer: new developments

C Gridelli - Current Opinion in Oncology, 2007 - journals.lww.com
Lung cancer is the leading cause of cancer-related mortality in both men and women [1],
with 1.2 million new cases diagnosed every year and with 1 million deaths being recorded …

Targeted therapies and non-small cell lung cancer: methodological and conceptual challenge for clinical trials

F Perrone, M Di Maio, A Budillon… - Current opinion in …, 2005 - journals.lww.com
Recent advances will lead to a rapid expansion of further studies aimed to define the best
way to use targeted agents in NSCLC. Several methodological issues are still open. The …

Treatment of non-small cell lung cancer and targeted therapies: where are we?

C Gridelli, A Rossi, P Maione - Current Opinion in Oncology, 2005 - journals.lww.com
Conventional treatment of non–small cell lung cancer (NSCLC) has reached a plateau in
improving patient survival, with overall disappointing results. Advances in the singling out of …

Targeted therapy vs chemotherapy: which has had more impact on survival in lung cancer? Does targeted therapy make patients live longer? Hard to prove, but …

DR Camidge - Clinical Advances in Hematology & Oncology: H&O, 2014 - europepmc.org
Over the last few years, the use of molecular profiling to direct patients to specific targeted
therapies has irrevocably changed how we treat lung cancer. Despite this, many …

Targeted therapies for advanced non-small-cell lung cancer: current status and future implications

A Custodio, M Méndez, M Provencio - Cancer treatment reviews, 2012 - Elsevier
Lung cancer remains the leading cause of malignancy-related mortality worldwide, with over
one million cases diagnosed yearly. Non-small-cell lung cancer (NSCLC) accounts for> …

Targeted therapy in advanced non-small cell lung cancer: current advances and future trends

U Majeed, R Manochakian, Y Zhao, Y Lou - Journal of hematology & …, 2021 - Springer
Lung cancer remains the leading cause of cancer-related mortality in both men and women
in the US and worldwide. Non-small cell lung cancer is the most common variety accounting …

Updated views in targeted therapy in the patient with non-small cell lung cancer

MA Ortega, L Pekarek, F Navarro… - Journal of Personalized …, 2023 - mdpi.com
Non-small cell lung cancer (NSCLC) is the most frequent form of lung cancer and represents
a set of histological entities that have an ominous long-term prognosis, for example …