Possible mechanisms for the renoprotective action of adipose-derived mesenchymal stem cells with CD44-targeted hyaluronic acid against renal ischemia

A Awadalla, AM Hussein, M Ali, N Barakat, ET Hamam… - Life Sciences, 2021 - Elsevier
The present study aimed to investigate the invitro preconditioning of adipose-derived
mesenchymal stem cells (ADMSCs) with CD44-targeted hyalournic acid (HA) on ischemic …

[HTML][HTML] Adipose-derived mesenchymal stem cell protects kidneys against ischemia-reperfusion injury through suppressing oxidative stress and inflammatory reaction

YT Chen, CK Sun, YC Lin, LT Chang, YL Chen… - Journal of translational …, 2011 - Springer
Background Reactive oxygen species are important mediators exerting toxic effects on
various organs during ischemia-reperfusion (IR) injury. We hypothesized that adipose …

Human Adipose Tissue-Derived Stromal Cells Ameliorate Adriamycin-Induced Nephropathy by Promoting Angiogenesis

X Zhao, C Ma, L Li, Y Yang, S Zhang, X Wang - Organogenesis, 2024 - Taylor & Francis
This study is to investigate the therapeutical effect and mechanisms of human-derived
adipose mesenchymal stem cells (ADSC) in relieving adriamycin (ADR)-induced …

Adipose-derived mesenchymal stem cells protects renal function in a rat model of emphysema

K Hoseinynejad, M Radan, M Dianat, F Nejaddehbashi - Tissue and Cell, 2021 - Elsevier
Background and objective The link between lung disease and kidney disorders has already
been confirmed. Previous studies have documented that obstructive pulmonary disease is …

[HTML][HTML] Protective effect of adipose-derived mesenchymal stem cells against acute kidney injury induced by ischemia-reperfusion in Sprague-Dawley rats

H Sheashaa, A Lotfy, F Elhusseini… - Experimental and …, 2016 - spandidos-publications.com
Acute kidney injury (AKI) is a complex clinical condition associated with significant morbidity
and mortality and lacking effective management. Ischemia‑reperfusion injury (IRI) remains …

Renoprotective effect of bone marrow mesenchymal stem cells with hyaluronic acid against adriamycin-induced kidney fibrosis via inhibition of Wnt/β-catenin pathway

WM Serag, N Barakat, ME Elshehabi, HS Hafez… - International Journal of …, 2022 - Elsevier
Aim The current study aimed to explore the pretreatment of bone marrow mesenchymal stem
cells (BMSCs) with hyaluronic acid (HA) on renal fibrosis in Adriamycin-induced CKD in rats …

[HTML][HTML] The effect of adipose-derived mesenchymal stem cells on renal function and histopathology in a rat model of ischemia-reperfusion induced acute kidney injury

S Changizi-Ashtiyani, L Hafazeh… - Iranian Journal of …, 2020 - ncbi.nlm.nih.gov
Objective (s): It has been shown that adipose-derived mesenchymal stem cells (AD-MSC)
have protective effects in acute kidney injury (AKI). This study was conducted to assess the …

[HTML][HTML] Cyclosporine-assisted adipose-derived mesenchymal stem cell therapy to mitigate acute kidney ischemia–reperfusion injury

YT Chen, CC Yang, YY Zhen, CG Wallace… - Stem cell research & …, 2013 - Springer
Introduction This study tested the hypothesis that cyclosporine (CsA)-supported syngeneic
adipose-derived mesenchymal stem cell (ADMSC) therapy offered superior attenuation of …

[HTML][HTML] Modulation of renal parenchyma in response to allogeneic adipose-derived mesenchymal stem cells transplantation in acute kidney injury

S Begum, N Ahmed, M Mubarak… - … journal of stem …, 2019 - synapse.koreamed.org
Methods and Results The nephrotoxicity was induced by cisplatin (CP) in balb/c mice
according to RIFLE Class and AKIN Stage 3. PCR, qRT-PCR and fluorescent labeled cells …

Kidney extracellular matrix hydrogel enhances therapeutic potential of adipose-derived mesenchymal stem cells for renal ischemia reperfusion injury

C Zhou, L Zhou, J Liu, L Xu, Z Xu, Z Chen, Y Ge… - Acta biomaterialia, 2020 - Elsevier
Stem cell-based therapy has been suggested as a promising option for the treatment of
renal ischemia-reperfusion injury (IRI). However, how to efficiently deliver stem cells remains …