Neuronal basis of non-invasive functional imaging: from microscopic neurovascular dynamics to BOLD fMRI

A Devor, DA Boas, GT Einevoll, RB Buxton… - Neural metabolism in …, 2012 - Springer
With the growing recognition of the complexity of neurovascular coupling, research has
focused on the “neurovascular unit”, a close association between neurons, astrocytes and …

Toward an integrative neurovascular framework for studying brain networks

J Guilbert, A Légaré, P De Koninck… - …, 2022 - spiedigitallibrary.org
Brain functional connectivity based on the measure of blood oxygen level-dependent
(BOLD) functional magnetic resonance imaging (fMRI) signals has become one of the most …

[HTML][HTML] Neurovascular coupling

BN Pasley, RD Freeman - Scholarpedia, 2008 - var.scholarpedia.org
Neurovascular coupling refers to the relationship between local neural activity and
subsequent changes in cerebral blood flow (CBF). The magnitude and spatial location of …

[HTML][HTML] A multi-compartment vascular model for inferring arteriole dilation and cerebral metabolic changes during functional activation

TJ Huppert, MS Allen, H Benav, A Devor… - Journal of cerebral …, 2007 - ncbi.nlm.nih.gov
Functional hemodynamic responses, measured by methods such as fMRI or optical imaging,
are the composite, downstream results of underlying variations in cerebral oxygen …

Key relationships between non-invasive functional neuroimaging and the underlying neuronal activity

A Mishra, CN Hall, C Howarth… - … Transactions of the …, 2021 - royalsocietypublishing.org
Functional neuroimaging using MRI relies on measurements of blood oxygen level-
dependent (BOLD) signals from which inferences are made about the underlying neuronal …

Recent advances in high-resolution MR application and its implications for neurovascular coupling research

N Harel, PJ Bolan, R Turner, K Ugurbil… - Frontiers in …, 2010 - frontiersin.org
The current understanding of fMRI, regarding its vascular origins, is based on numerous
assumptions and theoretical modeling, but little experimental validation exists to support or …

Neurovascular coupling

B Weber - fMRI: From nuclear spins to brain functions, 2015 - Springer
The brain consumes approximately a quarter of the body's total glucose and a fifth of the
oxygen, much more than what would be expected on a weight basis. This remarkable …

Translating the hemodynamic response: why focused interdisciplinary integration should matter for the future of functional neuroimaging

S Cinciute - PeerJ, 2019 - peerj.com
The amount of information acquired with functional neuroimaging techniques, particularly
fNIRS and fMRI, is rapidly growing and has enormous potential for studying human brain …

Coupling between neuronal activity and microcirculation: implications for functional brain imaging

I Vanzetta, A Grinvald - HFSP journal, 2008 - Taylor & Francis
In the neocortex, neurons with similar response properties are often clustered together in
column‐like structures, giving rise to what has become known as functional architecture …

Simple explanations before complex theories: Alternative interpretations of Sirotin and Das' observations

DA Handwerker, PA Bandettini - Neuroimage, 2011 - Elsevier
We make a few additional points regarding our discussion with Sirotin and Das' 2009 Nature
paper and their 2011 NeuroImage response to our commentary. While we find their data …