Improved isolation and culture of urine-derived stem cells (USCs) and enhanced production of immune cells from the USC-derived induced pluripotent stem cells

K Kim, M Gil, AA Dayem, S Choi, GH Kang… - Journal of Clinical …, 2020 - mdpi.com
The availability of autologous adult stem cells is one of the essential prerequisites for human
stem cell therapy. Urine-derived stem cells (USCs) are considered as desirable cell sources …

Generation of urine-derived induced pluripotent stem cell line from patients with acute kidney injury

Y Jin, M Zhang, M Li, H Zhang, F Zhang… - Cellular …, 2021 - liebertpub.com
Acute kidney injury (AKI) is mainly characterized by rapid decline of renal function. Currently,
the strategy of stem cells might be a therapy to treat AKI. The objective of this study was to …

[PDF][PDF] Optimized approaches for generation of integration-free iPSCs from human urine-derived cells with small molecules and autologous feeder

D Li, L Wang, J Hou, Q Shen, Q Chen, X Wang, J Du… - Stem Cell Reports, 2016 - cell.com
Generation of induced pluripotent stem cells (iPSCs) from human urine-derived cells (hUCs)
provides a convenient and non-invasive way to obtain patient-specific iPSCs. However …

Therapeutic potential of human induced pluripotent stem cells and renal progenitor cells in experimental chronic kidney disease

PC Ribeiro, FH Lojudice… - Stem cell research & …, 2020 - Springer
Background Chronic kidney disease (CKD) is a global public health problem. Cell therapy
using pluripotent stem cells represents an attractive therapeutic approach for the treatment …

Generation of induced nephron progenitor-like cells from human urine-derived cells

WW Gao, J Zheng, W Yun, PJ Kang, G Park… - International journal of …, 2021 - mdpi.com
Background: Regenerative medicine strategies employing nephron progenitor cells (NPCs)
are a viable approach that is worthy of substantial consideration as a promising cell source …

[HTML][HTML] Urine-derived stem/progenitor cells: a focus on their characterization and potential

P Burdeyron, S Giraud, T Hauet… - World journal of stem …, 2020 - ncbi.nlm.nih.gov
Cell therapy, ie., the use of cells to repair an affected tissue or organ, is at the forefront of
regenerative and personalized medicine. Among the multiple cell types that have been used …

Differentiation of human pluripotent stem cells into nephron progenitor cells in a serum and feeder free system

M Kang, YM Han - PloS one, 2014 - journals.plos.org
Objectives Kidney disease is emerging as a critical medical problem worldwide. Because of
limited treatment options for the damaged kidney, stem cell treatment is becoming an …

Urine-derived stem cells, a new source of seed cells for tissue engineering

P Gao, D Jiang, W Liu, H Li, Z Li - Current stem cell research & …, 2016 - ingentaconnect.com
Tissue engineering, as a frontier of medicine, is aimed at regeneration of tissue and organ
which can be used for the therapy of many diseases, such as trauma, cancer, and deformity …

Comparative analysis of human induced pluripotent stem cell‐derived mesenchymal stem cells and umbilical cord mesenchymal stem cells

S Rajasingh, V Sigamani, V Selvam… - Journal of Cellular …, 2021 - Wiley Online Library
Generation of induced pluripotent stem cells (iPSCs) and their differentiation into
mesenchymal stem/stromal cells (iMSCs) have created exciting source of cells for …

Urine-derived stem cells: applications in regenerative and predictive medicine

G Bento, AK Shafigullina, AA Rizvanov, VA Sardão… - Cells, 2020 - mdpi.com
Despite being a biological waste, human urine contains a small population of cells with self-
renewal capacity and differentiation potential into several cell types. Being derived from the …