Autoimmune myocarditis is not associated with left ventricular systolic dysfunction

M Mirna, V Paar, T Kraus, K Sotlar… - European Journal of …, 2019 - Wiley Online Library
Background Experimental autoimmune myocarditis (EAM) is a common animal model for the
investigation of the pathophysiology of myocarditis. Because of diverging findings from …

Activation of cardiac macrophages, endothelial cells and fibroblasts in experimental autoimmune myocarditis

K Tkacz, F Rolski, A Jazwa-Kusior… - European Heart …, 2022 - academic.oup.com
Abstract Background/Introduction Inflammation of cardiac tissue, termed myocarditis, is a
common cause of dilated cardiomyopathy associated with abnormal tissue remodeling …

Mortality and morbidity in different immunization protocols for experimental autoimmune myocarditis in rats

P Schmerler, S Jeuthe, DO h‐Ici, K Wassilew… - Acta …, 2014 - Wiley Online Library
Aim We aimed to investigate the histological and clinical presentations of experimental
autoimmune myocarditis (EAM) induced by different immunization schemes. Methods Male …

Regulation of inflammation and myocardial fibrosis in experimental autoimmune myocarditis

K Watanabe, V Sukumaran… - … & Allergy-Drug …, 2011 - ingentaconnect.com
Autoimmune responses and inflammation are involved in the pathogenesis of many
cardiovascular diseases. There is compelling evidence that inflammatory mechanisms may …

[HTML][HTML] Sex-specific differences of the inflammatory state in experimental autoimmune myocarditis

ML Barcena, S Jeuthe, MH Niehues… - Frontiers in …, 2021 - frontiersin.org
Increasing evidence suggests male sex as a potential risk factor for a higher incidence of
cardiac fibrosis, stronger cardiac inflammation, and dilated cardiomyopathy (DCM) in human …

Alterations in cardiac function and gene expression during autoimmune myocarditis in mice

LB Stull, NA DiIulio, M Yu, CF McTiernan… - Journal of Molecular and …, 2000 - Elsevier
LB Stull, NA DiIulio, M. Yu, CF McTiernan, NB Ratliff, VK Tuohy and C. Schomisch Moravec.
Alterations in Cardiac Function and Gene Expression during Autoimmune Myocarditis in …

Animal models of autoimmune myocarditis

M Kodama, Y Okura, Y Aizawa, T Izumi - Myocarditis: From Bench to …, 2003 - Springer
Myocarditis is defined pathologically as an inflammation of the heart muscle. There are 2
major challenges in the field of myocarditis. One is that patients with severe forms of …

The effect of intravenous immunoglobulins on the progression of experimental autoimmune myocarditis in the rat

J George, I Barshack, E Malka, I Goldberg… - … and molecular pathology, 2001 - Elsevier
The aim of this study was to evaluate the efficacy of two experimental regimes of human
intravenous immunoglobulins (IVIG) on the progression of experimental autoimmune …

Chronic myocarditis induced by T cells reactive to a single cardiac myosin peptide: persistent inflammation, cardiac dilatation, myocardial scarring and continuous …

NR Ratcliffe, J Hutchins, B Barry, WF Hickey - Journal of autoimmunity, 2000 - Elsevier
Recent recognition that an autoimmune myocarditis may precede, and result in, dilated
cardiomyopathy has focused attention on immune mechanisms of myocardial injury. In this …

Experimental rat model representing both acute and chronic heart failure related to autoimmune myocarditis

S Koyama, M Kodama, T Izumi, A Shibata - Cardiovascular drugs and …, 1995 - Springer
The most important clinical manifestation of myocarditis is congestive heart failure. The
precise mechanisms of heart failure during myocarditis have not been elucidated because …