Higher stages of central auditory processing compensate for a loss of cochlear nerve
synapses by increasing the gain on remaining afferent inputs, thereby restoring firing rate …

Kv3. 1b channel protein is widely distributed in the mammalian auditory brainstem, but
studies have focused mainly on regions critical for temporal processing, including the medial …

Many rapidly firing neurons, including those in the medial nucleus of the trapezoid body
(MNTB) in the auditory brain stem, express “high threshold” voltage-gated Kv3. 1 potassium …

The central auditory brainstem provides an efferent projection known as the medial
olivocochlear (MOC) system, which regulates the cochlear amplifier and mediates protection …

Tinnitus, the perception of phantom sound, is often a debilitating condition that affects many
millions of people. Little is known, however, about the molecules that participate in the …

Damage to sensory organs triggers compensatory plasticity mechanisms in sensory cortices.
These plasticity mechanisms result in restored cortical responses, despite reduced …

Age-related hearing loss (ARHL) is the most common sensory impairment mainly caused by
degeneration of sensory hair cells in the cochlea with no causal medical treatment available …

Abstract Kv7. 5/KCNQ5, a voltage‐dependent potassium channel that generates a
subthreshold K+ current (also called M‐current), is localized in excitatory endings of auditory …

Exposure to loud noise can cause hearing loss and tinnitus in mice and humans. In mice,
one major underlying mechanism of noise-induced tinnitus is hyperactivity of auditory …

The acoustic environment contains biologically relevant information on timescales from
microseconds to tens of seconds. The auditory brainstem nuclei process this temporal …