Chemokines and their receptors play an important role in the recruitment, activation and
differentiation of immune cells. The chemokine receptor, CXCR3, and its ligands, CXCL9 …

Recruitment of activated T‐cells to the skin is a common feature in a wide variety of
inflammatory skin diseases. As CXCR3 activating chemokines CXCL10 (IP‐10), CXCL9 …

First thought to orchestrate exclusively leukocyte trafficking, chemokines are now
acknowledged for their multiple roles in the regulation of cell proliferation, differentiation …

CXC chemokines are involved in chemotaxis, regulation of cell growth, induction of
apoptosis and modulation of angiostatic effects. CXCL9, CXCL10, CXCL11, CXCL4 and its …

CXCR3 is a chemokine receptor with three ligands; CXCL9, CXCL10, and CXCL11.
CXCL11 binds CXCR3 with a higher affinity than the other ligands leading to receptor …

Chemokines, binding their various G protein-coupled receptors, lead the way for leukocytes
in health and inflammation. Yet chemokine receptor expression is not limited to leukocytes …

Chemokines are a class of small cytokines or signaling proteins that are secreted by cells.
Owing to their ability to induce directional chemotaxis of nearby responding cells, they are …

Chemokine CXC motif ligand 13 (CXCL13), originally identified as a B-cell chemokine, plays
an important role in the immune system. The interaction between CXCL13 and its receptor …

Chemokines are small molecules called “chemotactic cytokines” and regulate many
processes like leukocyte trafficking, homing of immune cells, maturation, cytoskeletal …

CXCR3 is a G-protein coupled receptor which binds to ELR-negative CXC chemokines that
have been found to impact immune responses, vascular develop, and wound repair. More …