Acute diffusion tensor and kurtosis imaging and outcome following mild traumatic brain injury

J Stenberg, L Eikenes, KG Moen, A Vik… - Journal of …, 2021 - liebertpub.com
In this prospective cohort study, we investigated associations between acute diffusion tensor
imaging (DTI) and diffusion kurtosis imaging (DKI) metrics and persistent post-concussion …

Individual prediction of white matter injury following traumatic brain injury

PJ Hellyer, R Leech, TE Ham, V Bonnelle… - Annals of …, 2013 - Wiley Online Library
Objective Traumatic brain injury (TBI) often results in traumatic axonal injury (TAI). This can
be difficult to identify using conventional imaging. Diffusion tensor imaging (DTI) offers a …

Longitudinal diffusion tensor imaging detects recovery of fractional anisotropy within traumatic axonal injury lesions

BL Edlow, WA Copen, S Izzy, A van der Kouwe… - Neurocritical care, 2016 - Springer
Background Traumatic axonal injury (TAI) may be reversible, yet there are currently no
clinical imaging tools to detect axonal recovery in patients with traumatic brain injury (TBI) …

[HTML][HTML] High angular resolution diffusion-weighted imaging in mild traumatic brain injury

M Mohammadian, T Roine, J Hirvonen, T Kurki… - NeuroImage: Clinical, 2017 - Elsevier
We sought to investigate white matter abnormalities in mild traumatic brain injury (mTBI)
using diffusion-weighted magnetic resonance imaging (DW-MRI). We applied a global …

[HTML][HTML] Current opportunities for clinical monitoring of axonal pathology in traumatic brain injury

PP Tsitsopoulos, S Abu Hamdeh, N Marklund - Frontiers in neurology, 2017 - frontiersin.org
Traumatic brain injury (TBI) is a multidimensional and highly complex disease commonly
resulting in widespread injury to axons, due to rapid inertial acceleration/deceleration forces …

Quantitative assessments of traumatic axonal injury in human brain: concordance of microdialysis and advanced MRI

S Magnoni, CL Mac Donald, TJ Esparza, V Conte… - Brain, 2015 - academic.oup.com
Axonal injury is a major contributor to adverse outcomes following brain trauma. However,
the extent of axonal injury cannot currently be assessed reliably in living humans. Here, we …

Longitudinal changes of white matter microstructure following traumatic brain injury in US military service members

PH Yeh, SM Lippa, TA Brickell, J Ollinger… - Brain …, 2022 - academic.oup.com
The purpose of this study was to analyze quantitative diffusion tensor imaging measures
across the spectrum of traumatic brain injury severity and evaluate their trajectories in …

Evaluating neuroimaging sensitivities to alterations in structural connectivity following mild traumatic brain injury

J Sevick - 2022 - open.library.ubc.ca
Background: Advanced magnetic resonance imaging (MRI) techniques, including diffusion
tensor imaging (DTI) and myelin water imaging (MWI), are commonly used to assess the …

Diffusion-Weighted MRI Characterization of White Matter Injury Produced by Axon-Sparing Demyelination and Contusion Spinal Cord Injury in Rats

JF Talbott, Y Nout, M Wendland, P Mukherjee… - archive.ismrm.org
Recent literature suggests that diffusion weighted imaging may distinguish demyelination
from white matter injury with associated axon injury, thus serving as a powerful in-vivo …

Imaging biomarkers of vascular and axonal injury are spatially distinct in chronic traumatic brain injury

M Haber, F Amyot, CE Lynch… - Journal of Cerebral …, 2021 - journals.sagepub.com
Traumatic Brain Injury (TBI) is associated with both diffuse axonal injury (DAI) and diffuse
vascular injury (DVI), which result from inertial shearing forces. These terms are often used …