Estrogen receptor alpha and beta in health and disease

M Jia, K Dahlman-Wright, JÅ Gustafsson - Best practice & research Clinical …, 2015 - Elsevier
Estrogen receptors alpha (ERα) and beta (ERβ) are transcription factors that are involved in
the regulation of many complex physiological processes in humans. Abnormal ER signaling …

Regulation of estrogen receptor beta activity and implications in health and disease

E Swedenborg, KA Power, W Cai, I Pongratz… - Cellular and Molecular …, 2009 - Springer
Together with the estrogen receptor (ER) alpha, estrogen receptor beta (ERβ) mediates
many of the physiological effects of estrogens. As ERβ is crucially involved in a variety of …

[HTML][HTML] Estrogen signaling: a subtle balance between ERα and ERβ

J Matthews, JÅ Gustafsson - Molecular interventions, 2003 - triggered.edina.clockss.org
The biological actions of estrogens are mediated by estrogen binding to one of two specific
estrogen receptors (ERs) ERα and ERβ, which belong to the nuclear receptor superfamily, a …

Estrogen signaling via estrogen receptor β

C Zhao, K Dahlman-Wright, JÅ Gustafsson - Journal of Biological Chemistry, 2010 - ASBMB
Estrogens act by binding to and activating two estrogen receptors (ERs), ERα and ERβ.
Transcriptional regulation by ERs is controlled by a complex array of factors such as ER …

Estrogen receptor beta (ERβ): a ligand activated tumor suppressor

R Mal, A Magner, J David, J Datta… - Frontiers in …, 2020 - frontiersin.org
Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) belong to a superfamily of
nuclear receptors called steroid hormone receptors, which, upon binding ligand, dimerize …

Estrogen receptor β: an overview and update

C Zhao, K Dahlman-Wright… - Nuclear receptor …, 2008 - journals.sagepub.com
The discovery of a second estrogen receptor (ER), designated ERβ (NR3A2), has redefined
our knowledge about the mechanisms underlying cellular signaling by estrogens and has …

Role of estrogen receptors in health and disease

P Chen, B Li, L Ou-Yang - Frontiers in endocrinology, 2022 - frontiersin.org
Estrogen receptors (ERs) regulate multiple complex physiological processes in humans.
Abnormal ER signaling may result in various disorders, including reproductive system …

[HTML][HTML] Update on estrogen signaling

Z Weihua, S Andersson, G Cheng, ER Simpson… - FEBS letters, 2003 - Elsevier
Our understanding of estrogen signaling has undergone a true paradigm shift over recent
years, following the discovery in 1995 of a second estrogen receptor, estrogen receptor β …

Estrogen receptors alpha (ERα) and beta (ERβ): subtype-selective ligands and clinical potential

I Paterni, C Granchi, JA Katzenellenbogen, F Minutolo - Steroids, 2014 - Elsevier
Estrogen receptors alpha (ERα) and beta (ERβ) are nuclear transcription factors that are
involved in the regulation of many complex physiological processes in humans. Modulation …

[PDF][PDF] Loss of ERβ expression as a common step in estrogen-dependent tumor progression

A Bardin, N Boulle, G Lazennec… - Endocrine-related …, 2004 - erc.bioscientifica.com
The characterization of estrogen receptor beta (ERβ) brought new insight into the
mechanisms underlying estrogen signaling. Estrogen induction of cell proliferation is a …