The diagnosis of systemic vasculitis is challenging. Laboratory testing may provide useful
information. Routine laboratory tests include erythrocyte sedimentation rate (ESR), C …

Detection of antineutrophil cytoplasmic antibodies (ANCAs) is a well-established diagnostic
test used to evaluate suspected necrotizing vasculitis of small blood vessels. Conditions …

The Diagnostic and Classification Criteria in Vasculitis (DCVAS) study was developed in
order to overcome some major limitations of the ACR 1990 criteria of granulomatosis with …

Anti-neutrophil cytoplasmic antibodies (ANCA) are the hallmark of the so-called ANCA-
associated vasculitides (AAV)(Jennette & Falk, 1997). These primary small-vessel …

In the 1950s, the vasculitides associated with antineutrophil cytoplasmic antibodies
(ANCA)(Wegener's granulomatosis [WG], microscopic polyangiitis [MPA], and Churg-Strauss …

Vasculitides are a group of related disorders characterized by inflammation of blood vessels
leading to tissue or end-organ injury. However, the classification of vasculitis has been …

SIR, the ANCA-associated vasculitides (AAV) are rare inflammatory diseases. For the most
common subtype (granulomatosis with polyangiitis), the estimated prevalence varies …

Serological analysis has a central role in the diagnostic work-up of patients with suspected
small vessel vasculitis, both for establishing a specific diagnosis and for the monitoring of …

Antineutrophil cytoplasmic antibodies (ANCA) are autoantibodies directed against antigens
found in the cytoplasmic granules of neutrophils and monocytes. ANCA testing is usually …

Considerable progress has been made in understanding the role of autoantibodies in
systemic vasculitides (SV), and consequently testing for anti-neutrophil cytoplasmic …