The molecular and cellular mechanisms that underlie the many roles of macrophages in
health and disease states in vivo remain poorly understood. The purpose of this Review is to …

Embryo-derived tissue-resident macrophages are the first representatives of the
haematopoietic lineage to emerge in metazoans. In mammals, resident macrophages …

The important role of macrophages in host defense against a variety of pathogens has long
been recognized and has been documented and reviewed in numerous publications …

The origin of tissue-resident macrophages, crucial for homeostasis and immunity, has
remained controversial until recently. Originally described as part of the mononuclear …

Tissue-resident macrophages have been associated with important and diverse biological
processes such as native immunity, tissue homeostasis and angiogenesis during …

A literature covering 150 years of research indicates that macrophages are a diverse family
of professional phagocytes that continuously explore their environment, recognize and …

Monocytes and macrophages are critical effectors and regulators of innate immune
response. They not only play crucial and distinctive roles in homeostasis, but also contribute …

Monocytes and macrophages have crucial and distinct roles in tissue homeostasis and
immunity, but they also contribute to a broad spectrum of pathologies and are thus attractive …

Macrophages are cellular components of the innate immune system that reside in virtually
all tissues and contribute to immunity, repair, and homeostasis. The traditional view that all …

Tissue-resident macrophages have pivotal functions for tissue defense and homeostasis.
Two main discoveries have changed our current understanding of macrophage …