Emerging strategies for managing differentiated thyroid cancers refractory to radioiodine

S Bulotta, M Celano, G Costante, D Russo - Endocrine, 2016 - Springer
Efficient treatment of radio refractory thyroid cancer is still a major challenge. The recent
identification of genetic and epigenetic alterations present in almost all differentiated tumors …

Progress in treating advanced thyroid cancers in the era of targeted therapy

CC Lubitz, PM Sadow, GH Daniels, LJ Wirth - Thyroid, 2021 - liebertpub.com
Background: Thyroid cancer is a common malignancy whose detection has increased
significantly in past decades. Most of the increased incidence is due to detection of early …

Gene expression profiling associated with the progression to poorly differentiated thyroid carcinomas

JM Pita, A Banito, BM Cavaco, V Leite - British journal of cancer, 2009 - nature.com
Background: Poorly differentiated thyroid carcinomas (PDTC) represent a heterogeneous,
aggressive entity, presenting features that suggest a progression from well-differentiated …

Biologic and clinical perspectives on thyroid cancer

JA Fagin, SA Wells Jr - New England Journal of Medicine, 2016 - Mass Medical Soc
Biologic and Clinical Perspectives on Thyroid Cancer | New England Journal of Medicine Skip to
main content The New England Journal of Medicine homepage Advanced Search SEARCH …

Molecular analysis of thyroid tumors

F Bhaijee, YE Nikiforov - Endocrine pathology, 2011 - Springer
Thyroid cancer is the most common endocrine malignancy, and its incidence is rising in the
USA and other countries. Papillary and follicular thyroid carcinomas are the two most …

Molecular alterations in thyroid carcinoma

MRH Al Rasheed, B Xu - Surgical pathology clinics, 2019 - surgpath.theclinics.com
Thyroid carcinoma is the most common cancer in the endocrine system. Recent advances,
using next-generation sequencing, have shed light on the molecular pathogenesis of thyroid …

Molecular markers in well-differentiated thyroid cancer

AK D'Cruz, R Vaish, A Vaidya, IJ Nixon… - European Archives of …, 2018 - Springer
Purpose Thyroid nodules are of common occurrence in the general population. About a
fourth of these nodules are indeterminate on aspiration cytology placing many a patient at …

Genomic landscape of poorly differentiated and anaplastic thyroid carcinoma

B Xu, R Ghossein - Endocrine pathology, 2016 - Springer
Poorly differentiated thyroid carcinoma (PDTC) and anaplastic thyroid carcinoma (ATC) are
aggressive thyroid tumors associated with a high mortality rate of 38–57% and almost 100 …

Molecular pathogenesis and mechanisms of thyroid cancer

M Xing - Nature Reviews Cancer, 2013 - nature.com
Thyroid cancer is a common endocrine malignancy. There has been exciting progress in
understanding its molecular pathogenesis in recent years, as best exemplified by the …

Diagnosis and management of differentiated thyroid cancer using molecular biology

RL Witt, RL Ferris, EA Pribitkin, SI Sherman… - The …, 2013 - Wiley Online Library
Abstract Objectives/Hypothesis: To define molecular biology in clinical practice for
diagnosis, surgical management, and prognostication of differentiated thyroid cancer. Data …