[HTML][HTML] Advances and challenges in thyroid cancer: The interplay of genetic modulators, targeted therapies, and AI-driven approaches

S Bhattacharya, RK Mahato, S Singh, GK Bhatti… - Life Sciences, 2023 - Elsevier
Thyroid cancer continues to exhibit a rising incidence globally, predominantly affecting
women. Despite stable mortality rates, the unique characteristics of thyroid carcinoma …

[HTML][HTML] Radioiodine-refractory thyroid cancer: Molecular mechanisms and therapeutic strategies for radioiodine resistance

H Shen, R Zhu, Y Liu, Y Hong, J Ge, J Xuan… - Drug Resistance …, 2023 - Elsevier
Radioiodine refractory differentiated thyroid cancer (RAIR-DTC) is difficult to treat with
radioactive iodine because of the absence of the sodium iodide transporter (NIS) in the …

Molecular genetics and diagnosis of thyroid cancer

YE Nikiforov, MN Nikiforova - Nature Reviews Endocrinology, 2011 - nature.com
Thyroid cancer is a common type of endocrine malignancy, and its incidence has been
steadily increasing in many regions of the world. Initiation and progression of thyroid cancer …

Thyroid cancers: from surgery to current and future systemic therapies through their molecular identities

L Lorusso, V Cappagli, L Valerio, C Giani… - International Journal of …, 2021 - mdpi.com
Differentiated thyroid cancers (DTC) are commonly and successfully treated with total
thyroidectomy plus/minus radioiodine therapy (RAI). Medullary thyroid cancer (MTC) is only …

Meta-analysis and meta-review of thyroid cancer gene expression profiling studies identifies important diagnostic biomarkers

OL Griffith, A Melck, SJM Jones… - Journal of clinical …, 2006 - ascopubs.org
Purpose An estimated 4% to 7% of the population will develop a clinically significant thyroid
nodule during their lifetime. In many cases, preoperative diagnoses by needle biopsy are …

Update on molecular diagnostics in thyroid pathology: a review

B Alzumaili, PM Sadow - Genes, 2023 - mdpi.com
Thyroid nodules are quite common, and the determination of a nodule of concern is
complex, involving serum testing, radiology and, in some cases, pathological evaluation. For …

[HTML][HTML] A review of driver genetic alterations in thyroid cancers

F Khatami, SM Tavangar - Iranian Journal of Pathology, 2018 - ncbi.nlm.nih.gov
Thyroid cancer is a frequent endocrine-related malignancy with continuously increasing
incidence, and recently the development in understanding its molecular pathogenesis is …

[图书][B] Thyroid cancer: a comprehensive guide to clinical management

L Wartofsky, D Van Nostrand - 2006 - Springer
are new to this edition. The authors provide not only the The second edition of Thyroid
Cancer: A Comp-most current review of their respective areas, but also their hensive Guide …

Genomic alterations in thyroid cancer: biological and clinical insights

I Landa, ME Cabanillas - Nature Reviews Endocrinology, 2024 - nature.com
Tumours can arise from thyroid follicular cells if they acquire driver mutations that
constitutively activate the MAPK signalling pathway. In addition, a limited set of additional …

Current status and future perspectives in differentiated thyroid cancer

TY Kim, WG Kim, WB Kim… - Endocrinology and …, 2014 - synapse.koreamed.org
Thyroid cancer is increasing all over the world. The exact cause of this increase is still
debated and there are conflicting reports. Sophisticated molecular studies suggest that …