Rosuvastatin in the management of hyperlipidemia

JWM Cheng - Clinical therapeutics, 2004 - Elsevier
BACKGROUND:: Rosuvastatin is a new statin indicated to reduce elevated levels of total
cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglycerides and to increase …

Rosuvastatin: efficacy, safety and clinical effectiveness

H Soran, P Durrington - Expert opinion on pharmacotherapy, 2008 - Taylor & Francis
Background: Rosuvastatin is a fully synthetic statin developed by AstraZeneca. It is a
competitive inhibitor of 3-hydroxy-3-methyl-glutaryl-CoA reductase. Objective: We reviewed …

Rosuvastatin for the treatment of hypercholesterolemia

NS Culhane, SL Lettieri, JR Skae - … : The Journal of Human …, 2005 - Wiley Online Library
Rosuvastatin, a new hydrophilic 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase
inhibitor (statin), is approved as an adjunct to diet in patients with primary …

Rosuvastatin for the treatment of patients with hypercholesterolemia

PH Chong, BT Yim - Annals of Pharmacotherapy, 2002 - journals.sagepub.com
OBJECTIVE: To review the currently available information on rosuvastatin in the treatment of
primary hypercholesterolemia. DATA SOURCES: MEDLEY (2000–January 2001), MEDLIT …

Efficacy and safety of rosuvastatin in the management of dyslipidemia

P Rubba, G Marotta, M Gentile - Vascular Health and Risk …, 2009 - Taylor & Francis
Rosuvastatin is a synthetic statin that represents an advance in the pharmacologic and
clinical properties of statins. Relative to other statins, rosuvastatin possesses a greater …

Efficacy and safety of rosuvastatin in treatment of dyslipidemia

JM McKenney - American journal of health-system pharmacy, 2005 - academic.oup.com
Purpose. The chemistry, pharmacology, pharmacokinetics, drug interactions, clinical
efficacy, adverse effects, dosage and administration, and place in therapy of rosuvastatin are …

Rosuvastatin

CI Carswell, GL Plosker, B Jarvis - Drugs, 2002 - Springer
Abstract▴ Rosuvastatin is a hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase
inhibitor used in the treatment of patients with dyslipidaemia. Rosuvastatin is not extensively …

Rosuvastatin: a review of its effect on atherosclerosis

GM Keating, DM Robinson - American journal of cardiovascular drugs, 2008 - Springer
The HMG-CoA reductase inhibitor (statin) rosuvastatin (Crestor®) is widely available for use
in the management of dyslipidemia, and was recently approved in the US to slow the …

An evaluation of rosuvastatin: pharmacokinetics, clinical efficacy and tolerability

JR Crouse III - Expert Opinion on Drug Metabolism & Toxicology, 2008 - Taylor & Francis
Background: The HMG Co-A reductase inhibitors (statins) are the most efficacious agents for
lowering cholesterol. Statins reduce clinical cardiovascular events and are generally well …

Efficacy and safety of rosuvastatin and atorvastatin in patients with hypercholesterolemia and a high risk of coronary heart disease: a randomized, controlled trial

GG Schwartz, MA Bolognese, BP Tremblay… - American Heart …, 2004 - Elsevier
BACKGROUND: This double-blind, multicenter, randomized trial compared rosuvastatin and
atorvastatin for reducing low-density lipoprotein cholesterol (LDL-C) in adults with …