Although considered a passive process in the past, it is now known that falling asleep and
passing through its various stages is an active process that is governed by certain groups of …

Sleep is a global, complex state that can be defined behaviorally or cognitively. The state of
sleep and its spectrum of electrophysiologic correlates are affected by medications in many …

The current chapter provides a critical update on the effects of relevant psychotropic
substances on sleep. Reviewed substances comprise over-the-counter sleep medications …

SLEEP Sleep is a very important drive. Studies performed on rats at the University of
Chicago suggest that total sleep deprivation leads to death within weeks (1). Sleep is also …

Sleep and wake states encompass a complex interaction of neuronal networks, involving
multiple neurotransmitters with a delicate balance governing the transition from one state to …

Sleep and waking function are closely connected in a 24-hour rhythm. The central nervous
system (CNS) structures involved in the promotion of the waking state include neurons …

Insomnia, defined as difficulty falling asleep, staying asleep, and/or experiencing restorative
sleep with associated impairment or significant distress, is a common condition resulting in …

Different medications can have significant effects on sleep quality and/or quantity. When
prescribing medications it is important to be aware of these possible adverse effects of …

Increased attention to the prevalence of excessive sleepiness has led to a clear need to treat
this symptom, thus reinforcing the need for a greater understanding of the neurobiology of …

Despite its prevalence, insomnia remains poorly understood, mainly because of the lack of
clear scientific data supporting the many approaches used. Millions of sufferers turn instead …