INTRODUCTION: Pancreatic cancer remains the fourth leading cause of cancer-related
deaths with approximately 5% five-year survival and 3 months of median survival. The …

Pancreatic ductal adenocarcinoma (PDAC) has a high mortality rate due to lack of detection,
tendency to metastasize to the liver, and the absence of effective treatments. Consequently …

The proliferation and branching pattern of blood vessels and nerves is mediated during
development, in part, by the interaction between the Neuropilin‐2 (NRP2) receptor and its …

Abstract Introduction: Pancreatic Ductal Adenocarcinoma (PDAC) is an aggressive form of
cancer with a high mortality rate, primarily due to lack of effective treatment options. Current …

Neuropilin 2 (NRP2) is a transmembrane receptor protein that was first discovered on
neurons and then endothelial cells. On endothelial cells, it serves as co-receptor with the …

Abstract Purpose. Neuropilin-2 (NRP-2) is a coreceptor for vascular endothelial growth
factor (VEGF) on endothelial cells. NRP-2 is overexpressed in pancreatic ductal …

Abstract 2518 Introduction. Neuropilin-2 (NRP-2) is a co-receptor for vascular endothelial
growth factor (VEGF) on endothelial cells and increases the binding affinity and activity of …

Pancreatic cancer, one of the most fatal types of human cancers, includes several non‑
epithelial and stromal components, such as activated fibroblasts, vascular cells, neural cells …

Neuropilins (NRP s) have been described as receptors for class 3 semaphorins and
coreceptors for a plethora of ligands, such as members of the vascular endothelial growth …

Pancreatic ductal adenocarcinoma (PDAC) is a deadly malignancy that is characterized by a
high rate of mutations in the K-ras oncogene, the p53 tumor suppressor genes, and the p16 …