Nicotinic acetylcholine receptors on neurons are part of a gene family that includes nicotinic
acetylcholine receptors on skeletal muscles and neuronal αbungarotoxin-binding proteins …

L angley 1 postu! ated the exis-tence of a receptive substance'for nicotine in skeletal muscle,
which could mediate the effects of nicotine on muscle contraction. It took decades of work to …

Acetylcholine receptors that bind nicotine with high affinity but do not bind alpha-
bungarotoxin have recently been immunoaffinity purified from brains of chickens and rats …

Publisher Summary The neuronal nicotinic acetylcholine receptors are likely to be
oligomeric proteins composed of five subunits. If these receptors were all homo-oligomers …

A family of genes coding for proteins homologous to the alpha subunit of the muscle
nicotinic acetylcholine receptor has been identified in the rat genome. These genes are …

Three gene families of the ligand‐gated ion channel gene superfamily encode proteins
which bind cholinergic ligands:(1) nicotinic acetylcholine receptors (AChRs) from skeletal …

Abstract Four genes (alpha 2, alpha 3, alpha 4, and beta 2), which encode proteins
homologous to the Torpedo electric organ and vertebrate muscle nicotinic acetylcholine …

Publisher Summary During the past decade, the availability of radiolabeled nicotine with
high specific activity has led to the discovery and mapping of nicotine binding sites in the …

A new subunit, g2, of the neuronal nicotinic receptor family has been identified. This subunit
has the structural features of a non-agonist-binding subunit. We provide evidence that p2 …

The four kinds of subunits of the Torpedo californica nicotinic acetylcholine receptor have
been produced in various combinations by injecting Xenopus oocytes with the …