Endometriosis is a major cause of chronic pelvic pain and infertility. Activation of STAT3
appears central to the inflammatory phenotype of eutopic endometrium in women with …

Abstract STUDY QUESTION Are STAT3 signaling molecules differentially expressed in
endometriosis? SUMMARY ANSWER Levels of phospho-STAT3 and HIF1A, its downstream …

All cardinal events during the reproductive cycle, including ovulation, implantation, and
menstruation, are characterized by a profound tissue remodeling and an associated local …

STUDY QUESTION Is activation of signal transducer and activator of transcription 3 (STAT3)
via interleukin-6 (IL-6) trans-signaling involved in fibrosis of endometriosis? SUMMARY …

Adenomyosis is a benign uterine disease that causes dysmenorrhea, heavy menstrual
bleeding, and infertility; however, its pathophysiology remains unclear. Since signal …

The differentiation of endometrial stromal cells into decidual cells (decidualization) is critical
for embryo implantation, but the mechanisms remain poorly defined. Numerous paracrine …

Signal transducer and activator of transcription (STAT) proteins are critical for the regulation
of numerous biological processes. In cattle, microarray analyses identified STAT1 as a …

Problem How does hypoxia‐mediated downregulation of dual‐specificity phosphatase‐2
(DUSP2) promote the development of endometriotic lesions? Method of study The levels of …

Differentiation of human endometrium during the secretory phase of the menstrual cycle is
characterized by expression of a variety of genes implicated in the establishment and …

A molecular interaction between maternal endometrium and implanting conceptus can lead
to activation of a variety of transcription factors that regulate expression of several genes …