[PDF][PDF] Modulation of CUMS Induced Behaviour Deficits in Rats by Alpha Lipoic Acid: Possible Involvement of Dopaminergic and Serotonergic Neurotransmission

L Akotkar, U Aswar, R Patil, D Kumar, M Aswar… - Research …, 2022 - academia.edu
Purpose: Stress is an important factor having a high impact on psychological development
which alters emotion, cognition and related behavioural outputs. Alpha lipoic acid (ALA) is a …

[HTML][HTML] Antidepressant Effect of Alpha Lipoic Acid in Rats Exposed to Chronic Unpredictable Mild Stress: Putative Role of Neurotransmitters and 5HT3 Receptor

L Akotkar, U Aswar, R Patil, D Kumar, M Aswar… - Future …, 2023 - mdpi.com
Depression is a neuropsychiatric disorder characterized by altered emotion and cognition.
Alpha lipoic acid (ALA) is a potent natural antioxidant and exhibits neuroprotective effects …

Alpha-lipoic acid attenuates depressive symptoms in mice exposed to chronic unpredictable mild stress

Y Yusha'u, UA Muhammad, S Mustapha… - Journal of African …, 2021 - ajol.info
Background: Depression is the most common psychiatric illness that involves mood
disturbances affecting many brain regions. Despite many approaches available to treat …

Alpha-lipoic acid enhances short-term spatial memory of mice in open-space forced swim-induced depression mouse model

Y Yusha'u, UM Adam, AA Wahab… - Neuroscience …, 2021 - neuroscirn.org
Depression affects over 264 million people of all ages globally. Major depressive disorder
significantly and chronically reduced quality of life by its association with functional …

[HTML][HTML] Alpha-lipoic acid-role in improving both reserpine toxicity and paroxetine treatment in the cerebral cortex of albino rats; histological, ultrastructural …

SM Arisha - Beni-Suef University Journal of Basic and Applied …, 2022 - Springer
Background Reserpine is a monoamine depletory drug cause oxidative damage and used
to induce depression-like features in rodent model. Paroxetine is an antidepressant drug …

Investigation of alpha-lipoic acid effect on memory impairment considering strain-dependent differences in mice

E Ghafour-Boroujerdi, S Rahmani, N Sanadgol… - Life Sciences, 2021 - Elsevier
Aims Memory impairment is regarded as one of the most challenging neurological disorders.
The present study aimed to investigate behavioral and biochemical differences among …

The antipsychotic effects of omega-3 fatty acids in rats

MH Kokacya, US Copoglu, R Dokuyucu, S Inanir… - The American journal of …, 2015 - Elsevier
Background In humans, omega-3 fatty acids are necessary for cell membranes, brain
function and nerve transmission continuation. When animals are exposed to a new …

Dietary of n-3 polyunsaturated fatty acids influence neurotransmitter systems of rats exposed to unpredictable chronic mild stress

R Yang, MQ Zhang, Y Xue, R Yang, MM Tang - Behavioural Brain …, 2019 - Elsevier
Emerging evidence suggest that neuromodulators are the critical factor involved in
depression. This study aimed to investigate the effects of unpredictable chronic mild stress …

Effects of alpha‐lipoic acid in an animal model of mania induced by d‐amphetamine

DS Macêdo, CD Medeiros, RC Cordeiro… - Bipolar …, 2012 - Wiley Online Library
Macêdo DS, Medeiros CD, Cordeiro RC, Sousa FC, Santos JV, Morais TA, Hyphantis TN,
McIntyre RS, Quevedo J, Carvalho AF. Effects of alpha‐lipoic acid in an animal model of …

Lipoic acid effects on lipid peroxidation level, superoxide dismutase activity and monoamines concentration in rat hippocampus

PMP Ferreira, GCG Militão, RM Freitas - Neuroscience letters, 2009 - Elsevier
The purposes of the present work were to verify lipid peroxidation level, superoxide
dismutase (SOD) activity and monoamines (dopamine (DA), norepinephrine (NE), serotonin …