In obesity, there is increased nonadipose tissue as well as increased adiposity. The
increase of nonadipose tissue entails an increase in skeletal muscle mass. Recent data …

An increased fat content in skeletal muscle appears to be a key structural abnormality in
obese individuals. Our recent observations, which entailed a cross-sectional comparison of …

The regulation of the selection of appropriate fuels by skeletal muscle is important both in
terms of muscle energy metabolism and also in the regulation of whole-body fuel supply and …

The composition and biochemistry of skeletal muscle are altered in obesity and type 2
diabetes mellitus (DM) as compared to nonobese individuals. In health, skeletal muscle has …

▪ Abstract Skeletal muscle contains the majority of the body's glycogen stores and a similar
amount of readily accessible energy as intramyocellular triglyceride (imTG). While a number …

The alarming increase in obesity and associated type 2 diabetes mellitus (T2DM) is a
paramount public health concern in developing countries. Skeletal muscle insulin resistance …

Although skeletal muscle is recognized as a primary site of lipid utilization, the study of
muscle bioenergetics has focused mainly on carbohydrate, and consequently our …

Recent evidence derived from four independent methods indicates that an excess
triglyceride storage within skeletal muscle is linked to insulin resistance. Potential …

It has long been recognized that skeletal muscle can contain modest stores of triglyceride
and that this depot of fuel can make a major contribution to energy production during …

Obesity has emerged as one of the leading global health threats of the 21 st century. The
current worldwide pandemic has been triggered by lifestyle habits that promote …