New therapies for advanced thyroid cancer
D Laha, N Nilubol, M Boufraqech - Frontiers in endocrinology, 2020 - frontiersin.org
Thyroid cancer is the most common endocrine cancer. The discovery of new biomarkers for
thyroid cancer has significantly improved the understanding of the molecular pathogenesis …
thyroid cancer has significantly improved the understanding of the molecular pathogenesis …
[HTML][HTML] Molecular basis and targeted therapy in thyroid cancer: Progress and opportunities
L Zhang, Q Feng, J Wang, Z Tan, Q Li, M Ge - Biochimica et Biophysica …, 2023 - Elsevier
Thyroid cancer (TC) is the most prevalent endocrine malignant tumor. Surgery,
chemotherapy, radiotherapy, and radioactive iodine (RAI) therapy are the standard TC …
chemotherapy, radiotherapy, and radioactive iodine (RAI) therapy are the standard TC …
Evolving molecularly targeted therapies for advanced-stage thyroid cancers
KC Bible, M Ryder - Nature Reviews Clinical Oncology, 2016 - nature.com
Increased understanding of disease-specific molecular targets of therapy has led to the
regulatory approval of two drugs (vandetanib and cabozantinib) for the treatment of …
regulatory approval of two drugs (vandetanib and cabozantinib) for the treatment of …
Molecular alterations in thyroid cancer: from bench to clinical practice
E Tirrò, F Martorana, C Romano, SR Vitale, G Motta… - Genes, 2019 - mdpi.com
Thyroid cancer comprises different clinical and histological entities. Whereas differentiated
(DTCs) malignancies are sensitive to radioiodine therapy, anaplastic (ATCs) and medullary …
(DTCs) malignancies are sensitive to radioiodine therapy, anaplastic (ATCs) and medullary …
Novel targeted therapies and immunotherapy for advanced thyroid cancers
Thyroid cancer is a frequently encountered endocrine malignancy. Despite the favorable
prognosis of this disease, 15–20% of differentiated thyroid cancer (DTC) cases and most …
prognosis of this disease, 15–20% of differentiated thyroid cancer (DTC) cases and most …
Evolving approaches to patients with advanced differentiated thyroid cancer
BR Haugen, SI Sherman - Endocrine reviews, 2013 - academic.oup.com
Advanced differentiated thyroid cancer (DTC), defined by clinical characteristics including
gross extrathyroidal invasion, distant metastases, radioiodine (RAI) resistance, and avidity …
gross extrathyroidal invasion, distant metastases, radioiodine (RAI) resistance, and avidity …
Thyroid cancer: pathogenesis and targeted therapy
DA Liebner, MH Shah - Therapeutic advances in …, 2011 - journals.sagepub.com
Therapeutic options for advanced, unresectable radioiodine-resistant thyroid cancers have
historically been limited. Recent progress in understanding the pathogenesis of the various …
historically been limited. Recent progress in understanding the pathogenesis of the various …
Molecular markers guiding thyroid cancer management
C Nylén, R Mechera, I Maréchal-Ross, V Tsang… - Cancers, 2020 - mdpi.com
The incidence of thyroid cancer is rapidly increasing, mostly due to the overdiagnosis and
overtreatment of differentiated thyroid cancer (TC). The increasing use of potent preclinical …
overtreatment of differentiated thyroid cancer (TC). The increasing use of potent preclinical …
An update on molecular biology of thyroid cancers
O Omur, Y Baran - Critical reviews in oncology/hematology, 2014 - Elsevier
Differentiated thyroid cancer (DTC) is the most common endocrinological malignancy. There
are several histological variants such as papillary and follicular thyroid carcinoma. Many …
are several histological variants such as papillary and follicular thyroid carcinoma. Many …
Key signaling pathways in thyroid cancer
MA Zaballos, P Santisteban - Journal of Endocrinology, 2017 - joe.bioscientifica.com
Whole genome sequencing approaches have provided unprecedented insights into the
genetic lesions responsible for the onset, progression and dedifferentiation of various types …
genetic lesions responsible for the onset, progression and dedifferentiation of various types …