Methods: All ADR reports handled by the ADEM in 2014 were recorded anonymously and
analysed descriptively. results: A total of 484 ADRs were reported through the ADEM in …

The aim of this observational prospective study was to assess the incidence rate and the
characteristics of adverse drug reactions (ADRs) induced by amiodarone during the long …

OBJECTIVE: Drug-induced liver injury (DILI) is more often a challenge even for expert
clinicians. Presently, there are limited data about the epidemiology, because the real …

Almost all European pharmaceutical companies assess the causal relationship between an
adverse event and a drug, but this assessment is generally not included in individual …

Introduction: Use of herbal medicines (HMs) is widespread across the world, with many
people relying on HMs for their primary healthcare or using HMs in the context of a healthy …

Idiosyncratic drug-induced liver injury (DILI) is an underreported and underestimated
adverse drug reaction. Information on the documented hepatotoxicity of drugs has recently …

Acute hepatotoxicity is a rare but potentially fatal complication of amiodarone use. Although
oral long-term use of the drug is frequently complicated by an asymptomatic rise in serum …

Introduction Adverse event reporting patterns vary between countries, reflecting differences
in reporting culture, clinical practice and underlying patient populations. Japan collects …

Purpose For the purpose of pharmacovigilance, we sought to determine the best performing
laboratory threshold criteria to detect drug‐induced liver injury (DILI) in the electronic …

AIM: To inform clinicians on the level of hepatotoxic risk among antimycotics in the post-
marketing setting, following the marketing suspension of oral ketoconazole for drug-induced …