Sleep states comprise a constellation of physiologic and behavioral traits, and the
mechanisms by which sedative/hypnotic medications alter these traits remain unclear. Drugs …

Sleep states are comprised of a constellation of physiologic and behavioral traits, and the
mechanisms by which sedative-hypnotic medications alter these traits remain unclear …

With an astounding 10% to 15% of the United States population meeting criteria for an
insomnia disorder, 1, 2 insomnia is not only the most common sleep disorder in the …

Sleep is essential for our physical and mental well being. However, when novel hypnotic
drugs are developed, the focus tends to be on the marginal and statistically significant …

Issue: Unique neurotransmitters acting at specific hypothalamic neurons promote either
wakefulness or sleep. Drugs and diseases that modify neurotransmission at these sites can …

Pharmacological approaches to our understanding of sleep have been at the forefront of
sleep research for many years. Traditional techniques have included the use of …

Introduction: The disorder insomnia represents a relevant and frequent condition in clinical
care. Cognitive behavioral therapy of insomnia (CBT-I) is regarded as first line treatment …

Many recent discoveries in both laboratory and clinical settings have greatly increased our
understanding of sleep medicine and the relevant psychopharmacology. This timely book …

This review explores basic sleep physiology, the mechanism of action for each class of
hypnotic agents, their clinical application based on pharmacodynamic and pharmacokinetic …

The fundamental purpose of sleep remains one of the most compelling questions yet to be
answered in the area of neuroscience, if not all of biology. A pervasive behavior among …