The Cac1 subunit of histone chaperone CAF-1 organizes CAF-1-H3/H4 architecture and tetramerizes histones
The histone chaperone Chromatin Assembly Factor 1 (CAF-1) deposits tetrameric (H3/H4) 2
histones onto newly-synthesized DNA during DNA replication. To understand the …
histones onto newly-synthesized DNA during DNA replication. To understand the …
The Cac2 subunit is essential for productive histone binding and nucleosome assembly in CAF-1
Nucleosome assembly following DNA replication controls epigenome maintenance and
genome integrity. Chromatin assembly factor 1 (CAF-1) is the histone chaperone …
genome integrity. Chromatin assembly factor 1 (CAF-1) is the histone chaperone …
DNA-mediated association of two histone-bound complexes of yeast Chromatin Assembly Factor-1 (CAF-1) drives tetrasome assembly in the wake of DNA replication
Nucleosome assembly in the wake of DNA replication is a key process that regulates cell
identity and survival. Chromatin assembly factor 1 (CAF-1) is a H3-H4 histone chaperone …
identity and survival. Chromatin assembly factor 1 (CAF-1) is a H3-H4 histone chaperone …
Molecular architecture of yeast chromatin assembly factor 1
D Kim, D Setiaputra, T Jung, J Chung, A Leitner… - Scientific reports, 2016 - nature.com
Abstract Chromatin Assembly Complex 1 (CAF-1) is a major histone chaperone involved in
deposition of histone H3 and H4 into nucleosome. CAF-1 is composed of three subunits; …
deposition of histone H3 and H4 into nucleosome. CAF-1 is composed of three subunits; …
Insights into the molecular architecture and histone H3-H4 deposition mechanism of yeast Chromatin assembly factor 1
How the very first step in nucleosome assembly, deposition of histone H3-H4 as tetramers or
dimers on DNA, is accomplished remains largely unclear. Here, we report that yeast …
dimers on DNA, is accomplished remains largely unclear. Here, we report that yeast …
A DNA binding winged helix domain in CAF-1 functions with PCNA to stabilize CAF-1 at replication forks
Abstract Chromatin assembly factor 1 (CAF-1) is a histone H3–H4 chaperone that deposits
newly synthesized histone (H3–H4) 2 tetramers during replication-coupled nucleosome …
newly synthesized histone (H3–H4) 2 tetramers during replication-coupled nucleosome …
Yeast CAF-1 assembles histone (H3-H4)2 tetramers prior to DNA deposition
DD Winkler, H Zhou, MA Dar, Z Zhang… - Nucleic acids …, 2012 - academic.oup.com
Following acetylation, newly synthesized H3-H4 is directly transferred from the histone
chaperone anti-silencing factor 1 (Asf1) to chromatin assembly factor 1 (CAF-1), another …
chaperone anti-silencing factor 1 (Asf1) to chromatin assembly factor 1 (CAF-1), another …
Mechanistic insights into histone deposition and nucleosome assembly by the chromatin assembly factor-1
Eukaryotic chromatin is a highly dynamic structure with essential roles in virtually all DNA-
dependent cellular processes. Nucleosomes are a barrier to DNA access, and during DNA …
dependent cellular processes. Nucleosomes are a barrier to DNA access, and during DNA …
CAF-1-induced oligomerization of histones H3/H4 and mutually exclusive interactions with Asf1 guide H3/H4 transitions among histone chaperones and DNA
WH Liu, SC Roemer, AM Port… - Nucleic acids …, 2012 - academic.oup.com
Abstract Anti-silencing function 1 (Asf1) and Chromatin Assembly Factor 1 (CAF-1)
chaperone histones H3/H4 during the assembly of nucleosomes on newly replicated DNA …
chaperone histones H3/H4 during the assembly of nucleosomes on newly replicated DNA …
Spatiotemporal kinetics of CAF-1-dependent chromatin maturation ensures transcription fidelity during S-phase
B Chen, HK MacAlpine, AJ Hartemink… - Genome …, 2023 - genome.cshlp.org
Proper maintenance of epigenetic information after replication is dependent on the rapid
assembly and maturation of chromatin. Chromatin Assembly Complex 1 (CAF-1) is a …
assembly and maturation of chromatin. Chromatin Assembly Complex 1 (CAF-1) is a …