Evaluation of two modalities of perioperative treatment in the management of extremity and truncal soft tissue sarcomas: neoadjuvant concurrent chemoradiotherapy …

J Attal, B Cabarrou, T Valentin, JP Nesseler… - Strahlentherapie und …, 2021 - Springer
Purpose Patients with locally advanced grade 2–3 extremity/truncal soft tissue sarcomas
(STS) are at high risk of recurrence. The objective of this study was to assess the efficacy …

Overall survival advantage of chemotherapy and radiotherapy in the perioperative management of large extremity and trunk soft tissue sarcoma; a large database …

O Mahmoud, A Tunceroglu, R Chokshi… - Radiotherapy and …, 2017 - Elsevier
Purpose Intergroup 9514 reported promising outcomes with neoadjuvant
chemoradiotherapy for large extremity/trunk soft tissue sarcoma (ESTS). One decade later …

[HTML][HTML] Neoadjuvant chemoradiation compared with neoadjuvant radiation alone in the management of high-grade soft tissue extremity sarcomas

SZ Hazell, C Hu, SR Alcorn, KO Asiedu… - Advances in Radiation …, 2020 - Elsevier
Purpose Patients with large, high-grade soft tissue sarcomas are commonly treated with
aggressive limb preservation regimens. This study aimed to assess cancer control outcomes …

Long-term follow-up of patients receiving neoadjuvant treatment modalties for soft tissue sarcomas of the extremities

M Rauch, A Agaimy, S Semrau, A Willner, O Ott… - Cancers, 2021 - mdpi.com
Simple Summary Neoadjuvant radiotherapy has gained popularity as a treatment strategy
for locally advanced soft tissue sarcoma of the extremities. However, little is yet known about …

The impact of perioperative chemotherapy timing in conjunction with postoperative external-beam radiation therapy on extremity soft-tissue sarcomas outcome

O Mahmoud, A Dosch, D Kwon, JD Pitcher… - American journal of …, 2016 - journals.lww.com
Purpose: The perioperative management of primary extremity soft-tissue sarcomas (ESTS) is
multidisciplinary including radiation therapy and chemotherapy (CT). The interplay between …

Neoadjuvant chemotherapy in patients undergoing neoadjuvant radiation for trunk and extremity soft tissue sarcoma

GN Tortorello, CE Sharon, KL Ma… - Journal of Surgical …, 2023 - Wiley Online Library
Introduction Many patients with high‐risk soft tissue sarcoma (STS) develop distant
metastases. Meta‐analyses suggest that chemotherapy confers a small survival benefit …

Neoadjuvant chemoradiation compared to neoadjuvant radiation alone and surgery alone for Stage II and III soft tissue sarcoma of the extremities

KK Curtis, JB Ashman, CP Beauchamp, AJ Schwartz… - Radiation …, 2011 - Springer
Background Neoadjuvant chemoradiation (NCR) prior to resection of extremity soft tissue
sarcoma (STS) has been studied, but data are limited. We present outcomes with NCR using …

The role of neoadjuvant radiochemotherapy in the management of localized high-grade soft tissue sarcoma

M Kobus, S Roohani, F Ehret, A Flörcken, JK Striefler… - Radiation …, 2022 - Springer
Background Standard treatment of soft tissue sarcoma (STS) of the extremities includes limb-
sparing surgery combined with pre-or postoperative radiotherapy (RT). The role of …

Prognostic variables in patients with primary soft tissue sarcoma of the extremity and trunk treated with neoadjuvant radiotherapy or neoadjuvant sequential …

M Bedi, DM King, M Shivakoti, T Wang… - Radiation …, 2013 - Springer
Background Neoadjuvant radiotherapy (NRT) is an effective strategy to treat soft tissue
sarcomas (STS). However, the role of neoadjuvant chemoradiotherapy (NCRT) remains to …

Neoadjuvant sequential chemoradiotherapy versus radiotherapy alone for treatment of high-risk extremity soft tissue sarcoma: a single-institution experience

L Kılıç, M Ekenel, S Karabulut, F Ağaoğlu… - Contemporary …, 2017 - termedia.pl
Results: Median follow-up time was 37 months. The estimated 3-year overall and disease-
free survival rates for the whole patient group were 79%(95% CI: 67.0–86.4) and …