In vitro Therapie des Cholangiozellulären Karzinom mit dem pflanzlichen Alkaloid Capsaicin

AS Wutka - 2017 - ub01.uni-tuebingen.de
Das cholangiozelluläre Karzinom (CCC) ist nach dem hepatozellulären Karzinom (HCC) die
zweithäufigste maligne Neoplasie der Leber. Die chirurgische Resektion stellt bis dato das …

Capsaicin impairs carcinogenesis of human intra-and extrahepatic cholangiocarcinoma cells

A Wutka, V Palagani, M El Khatib… - Zeitschrift für …, 2014 - thieme-connect.com
Methods: We analyzed the effect of capsaicin by testing different dosages on CC's growth
and epithelial plasticity by using WST-1 assay, wound healing assay, invasion assay, colony …

Capsaicin treatment attenuates cholangiocarcinoma carcinogenesis

A Wutka, V Palagani, S Barat, X Chen, M El Khatib… - PloS one, 2014 - journals.plos.org
Capsaicin, the most abundant pungent molecule produced by pepper plants, represents an
important ingredient in spicy foods consumed throughout the world. Studies have shown that …

Capsaicin enhances the drug sensitivity of cholangiocarcinoma through the inhibition of chemotherapeutic-induced autophagy.

HZF Hong ZaiFa, ZWX Zhao WenXiu, YZY Yin ZhenYu… - 2015 - cabidigitallibrary.org
Cholangiocarcinoma (CCA), a devastating cancer with a poor prognosis, is resistant to the
currently available chemotherapeutic agents. Capsaicin, the major pungent ingredient found …

Anti‐metastatic activity of capsaicin and natural capsaicin‐like compounds in human lung adenocarcinoma

SD Richbart, NA Nolan, AT Akers… - The FASEB …, 2018 - Wiley Online Library
Lung adenocarcinoma (LAC) accounts for 65% of all non‐small cell lung cancer (NSCLC)
cases. A substantial proportion of LAC present with extrapulmonary and distant metastasis …

Application of capsaicin as a potential new therapeutic drug in human cancers

S Zhang, D Wang, J Huang, Y Hu… - Journal of clinical …, 2020 - Wiley Online Library
What is known and objective Capsaicin, the major active ingredient of chili pepper, may play
a “dual role” in tumourigenesis, acting as a carcinogen or as a cancer preventive agent. The …

Exploring the Potential of Capsaicin in Cancer Therapy: In Vitro and In Vivo Effects and Their Mechanism of Action

M Basumatary, A Talukdar - … : From Natural Sources to Biosynthesis and …, 2024 - Springer
Cancer is the second most major cause of human mortality globally, and according to the
International Agency for Research on Cancer (IARC), more than 19 million cancer cases are …

Correction: Capsaicin treatment attenuates cholangiocarcinoma carcinogenesis

A Wutka, V Palagani, S Barat, X Chen, M El Khatib… - Plos one, 2016 - journals.plos.org
Correction: Capsaicin Treatment Attenuates Cholangiocarcinoma Carcinogenesis | PLOS ONE
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Anti‐invasive and anti‐metastatic activity of capsaicin and natural capsaicin‐like compounds in lung adenocarcinoma

SD Richbart, NA Nolan, AT Akers, KC Brown… - The FASEB …, 2022 - Wiley Online Library
Lung adenocarcinoma (LAC) accounts for about 65% of all non‐small cell lung cancer
(NSCLC) cases. A considerable proportion of LAC patients present (in the clinic) with local …

Capsaicin inhibits proliferation and chemosensitizes gastric carcinoma cells to 5-Fluorouracil

G Kismali, M Alpay, O Meral, F Kosova, DU Cakir, T Sel - Cancer Research, 2014 - AACR
Abstract Background: Capsaicin (trans-8-methyl-N-vanillyl-6-nonenamide) is the principal
pungent component in hot peppers. The role of capsaicin in carcinogenic processes is quite …