We examined whether persistence of epigenetic DNA methylation (DNA-me) alterations at
specific loci over two different time points in people with diabetes are associated with …

Metabolic memory, the persistent benefits of early glycaemic control on preventing and/or
delaying the development of diabetic complications, has been observed in the Diabetes …

Aims/hypothesis Development of type 2 diabetes depends on environmental and genetic
factors. We investigated the epigenome-wide association of prevalent diabetes with DNA …

Inter-individual DNA methylation variations were frequently hypothesized to alter individual
susceptibility to Type 2 Diabetes Mellitus (T2DM). Sequence-influenced methylations were …

Epigenetic regulation has been postulated to affect glucose metabolism, insulin sensitivity
and the risk of type 2 diabetes. Therefore, we performed an epigenome-wide association …

We assessed whether epigenetic histone posttranslational modifications are associated with
the prolonged beneficial effects (metabolic memory) of intensive versus conventional …

Monozygotic (MZ) twin pair discordance for childhood-onset Type 1 Diabetes (T1D) is∼
50%, implicating roles for genetic and non-genetic factors in the aetiology of this complex …

DNA methylation (DNAm) has been found to show robust and widespread age-related
changes across the genome. DNAm profiles from whole blood can be used to predict human …

Epigenetic changes may contribute substantially to risks of diseases of aging. Previous
studies reported seven methylation variable positions (MVPs) robustly associated with …

Known genetic susceptibility loci for type 2 diabetes (T2D) explain only a small proportion of
heritable T2D risk. We hypothesize that DNA methylation patterns may contribute to variation …