The role of NOS3 (rs2070744) and GNB3 (rs5443) genes' polymorphisms in endothelial dysfunction pathway and carotid intima-media thickness in hypertensive …

A Sydorchuk, L Sydorchuk, A Gutnitska… - General Physiology …, 2023 - search.ebscohost.com
The mechanisms orchestrating the balance between nitric oxide and endothelium-derived
contracting factors, and genetic predisposition to endothelial dysfunction in hypertensive …

Endothelium function biomarkers and carotid intima-media thickness changes in relation to NOS3 (rs2070744) and GNB3 (rs5443) genes polymorphism in the …

AR Sydorchuk, LP Sydorchuk, AF Gutnitska… - Endocrine …, 2022 - sciendo.com
Objective. The aim of the present study was to clarify the endothelial function biomarkers
and carotid “intima media” thickness (IMT) changes in relation to GNB3 (rs5443) and NOS3 …

Association of endothelial nitric oxide synthase (eNOS) gene G894T polymorphism with hypertension risk and complications

AA ALrefai, MSE Habib, RI Yaseen, MK Gabr… - Molecular and cellular …, 2016 - Springer
This study evaluated the association of NOS3 polymorphisms with hypertension risk and
complications. eNOS (G894T) SNP was performed by RT-PCR on 70 hypertensive patients …

Influence of nitric oxide synthase gene polymorphism (G894T) on carotid artery intima-media thickness in adults: the Bogalusa Heart Study

AR Bhuiyan, W Chen, SR Srinivasan, J Rice… - Journal of the American …, 2007 - Elsevier
Nitric oxide generated by the vascular endothelial nitric oxide synthase (eNOS) plays an
important role in the regulation of vascular structure/function and blood pressure. However …

A common variant of endothelial nitric oxide synthase (Glu298Asp) is an independent risk factor for carotid atherosclerosis

G Lembo, N De Luca, C Battagli, G Iovino, A Aretini… - Stroke, 2001 - Am Heart Assoc
Background and Purpose—Endothelium-derived NO is formed from l-arginine by
endothelial NO synthase (eNOS) encoded by the NOS 3 gene on chromosome 7. Because …

Interaction of G-protein β3 Subunit and Nitric Oxide Synthase Gene Polymorphisms on Carotid Artery Intima-media Thickness in Young Adults: The Bogalusa Heart …

AR Bhuiyan, W Chen, SR Srinivasan… - American journal of …, 2008 - academic.oup.com
Background G-protein β3 subunit (GNB3) gene C825T and endothelial nitric oxide (eNOS)
gene G894T polymorphisms both influence arterial structure and function. However …

Genetic variations of the endothelial nitric oxide synthase gene are related to increased levels of C-reactive protein and macrophage-colony stimulating-factor in …

JP Lekakis, I Ikonomidis, M Tsibida… - Thrombosis and …, 2006 - thieme-connect.com
It was the objective of this study to investigate the relation between nitric oxide synthase
(NOS3) gene polymorphisms, vascular inflammation, endothelial function, and …

[PDF][PDF] Linkage of metabolic disorders, endothelial dysfunction and NOS3 (rs2070744) and GNB3 (rs5443) genes polymorphisms in hypertensive patients

A Sydorchuk, L Sydorchuk… - Biointerface …, 2022 - biointerfaceresearch.com
The vascular endothelium is one of the earliest damage-targeted hypertensive-mediated
organs. The study aims to analyze the link of metabolic disorders with endothelial …

Association between endothelial NO synthase polymorphisms and arterial properties in the general population

J Seidlerová, J Filipovský, O Mayer Jr, A Kučerová… - Nitric Oxide, 2015 - Elsevier
Objective Nitric oxide plays an important role in vascular biology. Several single nucleotide
polymorphisms (SNP) in the endothelial nitric oxide gene (NOS3) have been previously …

The role of inducible NOS2 gene polymorphism in the development of essential arterial hypertension

LV Topchieva, OV Balan, VA Korneeva… - Bulletin of Experimental …, 2019 - Springer
The risk of essential arterial hypertension was assessed in carriers of the NOS2 gene
variants (rs1800482 (-954G> C), rs3730017 (C> T)). In subjects carrying C allele …