Identification of prototypes from Ligustri Lucidi Fructus in rat plasma based on a data‐dependent acquisition and multicomponent pharmacokinetic study

Y Wang, K Feng, M Li, L Han, W Wang… - Biomedical …, 2020 - Wiley Online Library
The identification and quantization of traditional Chinese medicine (TCM) are a challenge
for researchers and industry. Using untargeted analytical methods, the in vivo detection and …

Application of UHPLC-ESI-Q-TOF-MS to identify multiple constituents in processed products of the herbal medicine Ligustri Lucidi Fructus

H Li, W Yao, Q Liu, J Xu, B Bao, M Shan, Y Cao… - Molecules, 2017 - mdpi.com
Ligustri Lucidi Fructus (LLF), the fruit of Ligustrum lucidum Ait.(Oleaceae), has been used as
a common herbal medicine in clinical practice in China for nearly 2000 years. In most cases …

Ligustri Lucidi Fructus, a traditional Chinese Medicine: comprehensive review of botany, traditional uses, chemical composition, pharmacology, and toxicity

M Cao, J Wu, Y Peng, B Dong, Y Jiang, C Hu… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Ligustri Lucidi Fructus (LLF) is one of the usual
Chinese herbs that has long been used with high therapeutic and condition value. LLF is …

A pre-classification strategy based on UPLC-Triple-TOF/MS for metabolic screening and identification of Radix glehniae in rats

S Wang, P Qi, N Zhou, M Zhao, W Ding, S Li… - Analytical and …, 2016 - Springer
Abstract Traditional Chinese Medicines (TCMs) have gained increasing popularity in
modern society. However, the profiles of TCMs in vivo are still unclear owing to their …

Pharmacokinetic comparison of nine bioactive components in rat plasma following oral administration of raw and wine‐processed Ligustri Lucidi Fructus by ultra‐high …

D Zhang, L Sun, H Li, Y Cui, S Liu, P Wu… - Journal of …, 2020 - Wiley Online Library
An accurate and sensitive ultra‐high‐performance liquid chromatography coupled with triple
quadrupole mass spectrometry method was established and validated for the determination …

Ligustri Lucidi Fructus as a traditional Chinese medicine: a review of its phytochemistry and pharmacology

L Gao, C Li, Z Wang, X Liu, Y You, H Wei… - Natural product …, 2015 - Taylor & Francis
Ligustri Lucidi Fructus (LLF) is the fruits of Ligustrum lucidum Ait.(Oleaceae). This review
based on nearly 80 literary sources discusses the knowledge of chemistry and biological …

A targeted strategy to identify untargeted metabolites from in vitro to in vivo: Rapid and sensitive metabolites profiling of licorice in rats using ultra-high performance …

M Huang, Z Cheng, L Wang, Y Feng, J Huang… - … of Chromatography B, 2018 - Elsevier
It is challenging to conduct in vivo metabolic study for traditional Chinese medicines (TCMs)
because of complex components, unpredictable metabolic pathways and low metabolite …

Derivative multiple reaction monitoring and single herb calibration approach for multiple components quantification of traditional Chinese medicine analogous …

Z Li, S Xiao, N Ai, K Luo, X Fan, Y Cheng - Journal of Chromatography A, 2015 - Elsevier
In comparison with monotherapy in western medicine, traditional Chinese medicine (TCM)
advocates combinational therapy for treating diseases and TCM formula is a representative …

Deciphering the differentiations of traditional Chinese medicine analogous formulae by parallel liquid chromatography-mass spectrometry coupled with microplate …

S Xiao, C Hao, N Ai, K Luo, X Wen, S Wang… - Analytical methods, 2014 - pubs.rsc.org
For traditional Chinese medicine (TCM), its most common application form is TCM formulae
that assemble herbs and other materials together to treat diseases. According to the shared …

Systematic characterization of the absorbed components of Ligustri Lucidi Fructus and their metabolic pathways in rat plasma by ultra‐high‐performance liquid …

D Zhang, L Xiong, L Fang, H Li, X Zhao… - Journal of …, 2021 - Wiley Online Library
Abstract Ligustri Lucidi Fructus is a dried and mature fruit of Ligustrum lucidum Ait., which
has the effects of nourishing liver and kidney. Herein, an accurate and sensitive method was …