Abstract Background Fractional Flow Reserve (FFR) is currently indicated as a first line
strategy for the functional assessment of intermediate coronary stenoses. However, the …

Background The recommended dosage of intracoronary adenosine in fractional flow reserve
(FFR) assessment is controversial. High-dose adenosine may overcome the biological …

Background Maximal hyperemia is the critical prerequisite for fractional flow reserve (FFR)
assessment. Despite intravenous (IV) adenosine currently being the recommended …

Aims Intravenous infusion of adenosine is the reference method to measure fractional flow
reserve (FFR). Intracoronary boluses are often used because of time and convenience, but …

Methods We included patients undergoing coronary angiography at our Division of
Cardiology from June 2008 to February 2019 for elective indication or recent acute coronary …

Background: Achievement of maximal hyperemia is mandatory for an accurate calculation of
fractional flow reserve (FFR) and it is obtained with adenosine given either as an …

Intravenous (IV) infusion of adenosine represents the gold standard for measuring fractional
flow reserve (FFR). However, IV adenosine is more expensive and time-consuming …

BACKGROUND: The achievement of maximal vasodilatation of the coronary microvessels is
mandatory for the accurate determination of fractional flow reserve (FFR); the optimal dosing …

Background—Measurement of fractional flow reserve (FFR) constitutes the current gold
standard to evaluate the hemodynamic significance of coronary stenoses. Limited data …

Aims Fractional flow reserve measurement is based upon achieving maximum hyperemia. A
40 microg intracoronary (IC) adenosine bolus sometimes seems insufficient, and we …