Management of gout following 2016/2017 European (EULAR) and British (BSR) guidelines: an interrupted time-series analysis in the United Kingdom
MD Russell, AI Rutherford, B Ellis, S Norton… - The Lancet Regional …, 2022 - thelancet.com
Background Following studies reporting sub-optimal gout management, European (EULAR)
and British (BSR) guidelines were updated to encourage the prescription of urate-lowering …
and British (BSR) guidelines were updated to encourage the prescription of urate-lowering …
Association between serum urate and flares in people with gout and evidence for surrogate status: a secondary analysis of two randomised controlled trials
LK Stamp, C Frampton, MB Morillon… - The Lancet …, 2022 - thelancet.com
Background Use of serum urate as a treatment target and outcome measure has become
controversial in view of the 2017 American College of Physicians guidelines, which …
controversial in view of the 2017 American College of Physicians guidelines, which …
12-month results from the real-life observational treat-to-target and tight-control therapy NOR-Gout study: achievements of the urate target levels and predictors of …
T Uhlig, LF Karoliussen, J Sexton, T Borgen… - RMD open, 2021 - rmdopen.bmj.com
Objectives Gout is often not adequately treated, and we aimed to apply urate lowering
treatment (ULT) combined with individual information to achieve target serum urate (sUA) in …
treatment (ULT) combined with individual information to achieve target serum urate (sUA) in …
[HTML][HTML] Global patterns of treat-to-serum urate target care for gout: systematic review and meta-analysis
CN Son, S Stewart, I Su, B Mihov, G Gamble… - Seminars in Arthritis and …, 2021 - Elsevier
Background: International rheumatology guidelines advocate a treat to serum urate target
(T2T) approach for gout management. While individual studies have reported regional and …
(T2T) approach for gout management. While individual studies have reported regional and …
Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study
Objectives To describe trends in the epidemiology of gout and patterns of urate-lowering
treatment (ULT) in the UK general population from 1997 to 2012. Methods We used the …
treatment (ULT) in the UK general population from 1997 to 2012. Methods We used the …
Improvement in the management of gout is vital and overdue: an audit from a UK primary care medical practice
E Cottrell, V Crabtree, JJ Edwards, E Roddy - BMC family practice, 2013 - Springer
Background Gout is estimated to affect 1.4% of adults in the UK. Appropriate and timely
management is essential to reduce the risk of further flares, complications, and to reduce …
management is essential to reduce the risk of further flares, complications, and to reduce …
Interventions to improve uptake of urate-lowering therapy in patients with gout: a systematic review
I Gill, N Dalbeth, F Goodyear-Smith - BJGP open, 2020 - bjgpopen.org
Background Gout treatment is suboptimal despite available therapy, with low levels of
initiation and persistence of urate-lowering therapy (ULT) in many patients. Aim To identify …
initiation and persistence of urate-lowering therapy (ULT) in many patients. Aim To identify …
Diagnosis and treatment for hyperuricemia and gout: a systematic review of clinical practice guidelines and consensus statements
Q Li, X Li, J Wang, H Liu, JSW Kwong, H Chen, L Li… - BMJ open, 2019 - bmjopen.bmj.com
Objectives Despite the publication of hundreds of trials on gout and hyperuricemia,
management of these conditions remains suboptimal. We aimed to assess the quality and …
management of these conditions remains suboptimal. We aimed to assess the quality and …
Serum urate as surrogate endpoint for flares in people with gout: a systematic review and meta-regression analysis
L Stamp, MB Morillon, WJ Taylor, N Dalbeth… - Seminars in arthritis and …, 2018 - Elsevier
Objectives The primary efficacy outcome in trials of urate lowering therapy (ULT) for gout is
serum urate (SU). The aim of this study was to examine the strength of the relationship …
serum urate (SU). The aim of this study was to examine the strength of the relationship …
Comparative safety of gout treatment strategies on cardiovascular outcomes using observational data: Clone-censor-weight target trial emulation approach
Background: We sought to examine the cardiovascular safety of intensive treat-to-target
serum urate strategies for gout using Medicare claims data linked to electronic health record …
serum urate strategies for gout using Medicare claims data linked to electronic health record …