The role of epigenetics in the pathophysiology of epilepsy

SM Nam, KO Cho - Neuropsychiatric Disorders and Epigenetics, 2017 - Elsevier
Epilepsy is a group of heterogeneous diseases sharing a common feature, seizures. Acute
seizures can induce neuronal death, massive gliosis, inflammation, and aberrant …

The role of epigenetics in the pathophysiology of epilepsy

KO Cho - Neuropsychiatric Disorders and Epigenetics, 2024 - Elsevier
Epilepsy is a group of heterogeneous diseases sharing a common feature, seizures. Acute
seizures can induce neuronal death, massive gliosis, inflammation, and aberrant …

Epigenetic mechanisms underlying human epileptic disorders and the process of epileptogenesis

IA Qureshi, MF Mehler - Neurobiology of disease, 2010 - Elsevier
The rapidly emerging science of epigenetics and epigenomic medicine promises to reveal
novel insights into the susceptibility to and the onset and progression of epileptic disorders …

Epigenetics and epilepsy

DC Henshall, K Kobow - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Epigenetic processes in the brain involve the transfer of information arising from short-lived
cellular signals and changes in neuronal activity into lasting effects on gene expression. Key …

A tale of two epiphenomena: the complex interplay of epigenetics and epilepsy

SB Foti, AJ Roskams - Underlying mechanisms of epilepsy …, 2011 - books.google.com
Epilepsy is a disorder primarily characterized by the spontaneous recurrence of unprovoked
seizures. Seizures can be triggered by multiple factors including genetic mutations, head …

[HTML][HTML] Epigenetic principles underlying epileptogenesis and epilepsy syndromes

K Conboy, DC Henshall, GP Brennan - Neurobiology of disease, 2021 - Elsevier
Epilepsy is a network disorder driven by fundamental changes in the function of the cells
which compose these networks. Driving this aberrant cellular function are large scale …

Epigenetic regulation in epilepsy: A novel mechanism and therapeutic strategy for epilepsy

S Chen, M Huang, D Xu, M Li - Neurochemistry International, 2023 - Elsevier
Epilepsy is a common neurological disorder characterized by recurrent seizures with
excessive and abnormal neuronal discharges. Epileptogenesis is usually involved in …

Epigenetics and epilepsy prevention: The therapeutic potential of adenosine and metabolic therapies

D Boison, JM Rho - Neuropharmacology, 2020 - Elsevier
Prevention of epilepsy and its progression remains the most urgent need for epilepsy
research and therapy development. Novel conceptual advances are required to …

Epigenetics in epilepsy

K Kobow, I Blümcke - Neuroscience letters, 2018 - Elsevier
Approximately 50 million people have epilepsy, making it the most common chronic and
severe neurological disease worldwide, with increased risk of mortality and psychological …

The epigenetics of epilepsy and its progression

RM Hauser, DC Henshall, FD Lubin - The Neuroscientist, 2018 - journals.sagepub.com
Epilepsy is a common and devastating neurological disorder characterized by recurrent and
unprovoked spontaneous seizures. One leading hypothesis for the development and …