Written for researchers and clinicians in neurology and neuroscience, this text offers a
bridge across the so-called translational divide, to cover innovative treatment strategies that …

Seizures, particularly when prolonged (status epilepticus) or repeated (pharmacoresistant
epilepsy), can damage the brain. Injury is found acutely in humans after status epilepticus …

Seizure disorders affect a significant percentage of the population, and researchers
worldwide continue to work toward a better understanding of what initiates, propagates, and …

Epilepsy encompasses a group of heterogeneous brain diseases that affect more than 50
million people worldwide. Epilepsy may have discernible structural, infectious, metabolic …

The field of genetic epilepsy has witnessed remarkable advancements leading to improved
diagnosis, prognosis, and management. This chapter provides a comprehensive overview of …

Epilepsy is one of the most prevalent serious neurological disorders worldwide. Genetic
research is making a major impact on epilepsy in terms of both clinical management and …

This article provides a succinct overview of sex differences in epilepsy and putative
molecular mechanisms underlying sex differences in seizure susceptibility in chemical …

The pharmacological treatment of epilepsy is purely symptomatic. Despite many decades of
intensive research, causal treatment of this common neurologic disorder is still unavailable …

Mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) is the most common
focal epilepsy in adults. It is characterized by alarming rates of pharmacoresistance …