The SARS-CoV-2 Omicron (B. 1.1. 529) variant exhibits altered pathogenicity, transmissibility, and fitness in the golden Syrian hamster model

S Yuan, ZW Ye, R Liang, K Tang, AJ Zhang, G Lu… - BioRxiv, 2022 - biorxiv.org
The newly emerging SARS-CoV-2 Omicron (B. 1.1. 529) variant first identified in South
Africa in November 2021 is characterized by an unusual number of amino acid mutations in …

SARS-CoV-2 omicron variant: epidemiological features, biological characteristics, and clinical significance

Y Guo, J Han, Y Zhang, J He, W Yu, X Zhang… - Frontiers in …, 2022 - frontiersin.org
The SARS-CoV-2 Omicron (B. 1.1529) variant was designated as a variant of concern (VOC)
by the World Health Organization (WHO) on November 26, 2021. Within two months, it had …

Comparing the Infectivity of Recent SARS-CoV-2 Omicron Sub-Variants in Syrian Hamsters

R Abdelnabi, R Lassaunière, P Maes, B Weynand… - Viruses, 2024 - mdpi.com
Since the emergence of the first omicron SARS-CoV-2 variant at the end of 2021, several
sub-variants have evolved and become predominant in the human population, showing …

A heterologous challenge rescues the attenuated immunogenicity of SARS-CoV-2 omicron BA. 1 variant in Syrian hamster model

J Ma, X Liu, M Zhou, P Chen, R Chen, J Wang… - Journal of …, 2023 - Am Soc Microbiol
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant is
becoming a dominant circulator and has several mutations in the spike glycoprotein, which …

Pathogenicity of SARS-CoV-2 Omicron BA. 1.1 in hamsters

JFW Chan, H Chu - EBioMedicine, 2022 - thelancet.com
New variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that have
acquired different mutations which modulate viral transmissibility, pathogenicity, and …

The SARS‐CoV‐2 Omicron variant and its multiple sub‐lineages: transmissibility, vaccine development, antiviral drugs, monoclonal antibodies, and strategies for …

RK Mohapatra, S Verma, V Kandi, AK Sarangi… - …, 2023 - Wiley Online Library
Abstract The Omicron (B. 1.1. 529), fifth variant of concern (VOC) of SARS‐CoV‐2, initially
identified following a steep increase in COVID‐19 cases in Southern Africa in November …

Convalescence from prototype SARS-CoV-2 protects Syrian hamsters from disease caused by the Omicron variant

KA Ryan, RJ Watson, KR Bewley, C Burton, O Carnell… - BioRxiv, 2021 - biorxiv.org
The mutation profile of the SARS-CoV-2 Omicron variant poses a concern for naturally
acquired and vaccine-induced immunity. We investigated the ability of prior infection with an …

Pathogenicity of SARS-CoV-2 Omicron (R346K) variant in Syrian hamsters and its cross-neutralization with different variants of concern

S Mohandas, PD Yadav, G Sapkal, AM Shete… - …, 2022 - thelancet.com
Summary Background SARS-CoV-2 Omicron variant is rampantly spreading across the
globe. We assessed the pathogenicity and immune response generated by BA. 1.1 sub …

[HTML][HTML] The omicron (B. 1.1. 529) SARS-CoV-2 variant of concern does not readily infect Syrian hamsters

R Abdelnabi, CS Foo, X Zhang, V Lemmens, P Maes… - Antiviral research, 2022 - Elsevier
The emergence of SARS-CoV-2 variants of concern (VoCs) has exacerbated the COVID-19
pandemic. End of November 2021, a new SARS-CoV-2 variant namely the omicron (B. 1.1 …

The contagious nature of SARS-CoV-2 omicron variant and vaccine efficacy

SA Khan, I Ahmad, W Khan, H Khan… - Advancements in Life …, 2023 - als-journal.com
Background: Since the first COVID-19 outbreak, variants of SARS-CoV-2 have continued to
dominate the global population. The repeated waves of emerging variants, each replacing …