Resolvin D1 (RvD1) suppresses inflammatory, postoperative, and neuropathic pain. The
present study assessed the roles and mechanisms of RvD1 in mechanical allodynia after …

Neuroinflammation induced by protruded nucleus pulposus (NP) has been shown to play a
significant role in facilitation of radicular pain. Resolvin D2 (RvD2), a novel member of …

Background Accumulating evidence indicates that spinal inflammatory and immune
responses play an important role in the process of radicular pain caused by intervertebral …

The current study aimed to investigate the role and underlying mechanism of Resolvin D1
(RvD1) alleviating spinal nerve ligation (SNL)-induced neuropathic pain (NP) and its …

Spinal cord injury (SCI) is a fatal and intractable disease accompanied by the comorbidity of
chronic neuropathic pain. Here, we purposed to explore the therapeutic effect and the …

Resolvins, a new family from the endogenous specialized pro-resolving mediators (SPMs),
promote the resolution of the inflammatory response. Resolvin D3 (RvD3), a …

Background Harnessing the actions of the resolvin pathways has the potential for the
treatment of a wide range of conditions associated with overt inflammatory signalling. Aspirin …

Accumulating evidence indicates that activation of spinal cord microglia plays an important
role in the genesis of neuropathic pain. Resolvin E1 (E1) is derived from omega-3 …

The purpose of the present study was to investigate the role of resolvin D1 (RvD1) in
cerebral ischemia/reperfusion (I/R) injury in rats and its mechanism. A total of 60 adult male …

Background: Several studies performed thus far indicate that neuroinflammation may be one
of the mechanisms underlying the pathogenesis of neuropathic pain (NP). Autophagy, as an …