Effect of differing levels of tobacco-specific nitrosamines in cigarette smoke on the levels of biomarkers in smokers

DL Ashley, RJ O'Connor, JT Bernert, CH Watson… - … , biomarkers & prevention, 2010 - AACR
Background: Smokers are exposed to significant doses of carcinogens, including tobacco-
specific nitrosamines (TSNA). Previous studies have shown significant global differences in …

Tobacco-specific nitrosamine exposures in smokers and nonsmokers exposed to cigarette or waterpipe tobacco smoke

G Radwan, SS Hecht, SG Carmella… - Nicotine & Tobacco …, 2012 - academic.oup.com
Introduction: The causal relationship between tobacco smoking and a variety of cancers is
attributable to the carcinogens that smokers inhale, including tobacco-specific nitrosamines …

Investigation of exposure biomarkers in human plasma following differing levels of tobacco-specific N-nitrosamines and nicotine in cigarette smoke

J Zhang, X Liu, B Shi, Z Yang, Y Luo, T Xu, D Liu… - Environmental …, 2022 - Elsevier
Tobacco-specific N-nitrosamines (TSNAs) are strong carcinogens widely found in tobacco
products, environmental tobacco smoke, lake, and wastewater. The main objective of this …

TSNA exposure: levels of NNAL among Canadian tobacco users

CD Czoli, D Hammond - Nicotine & Tobacco Research, 2015 - academic.oup.com
Introduction: Tobacco smoke contains more than 7,000 chemicals, including known
carcinogens, such as tobacco-specific nitrosamines (TSNAs). TSNA levels in cigarettes vary …

Determination of tobacco-specific N-nitrosamines in urine of smokers and non-smokers

D Kavvadias, G Scherer, F Cheung, G Errington… - Biomarkers, 2009 - Taylor & Francis
Tobacco-specific N-nitrosamines (TSNA) include 4-(methylnitrosamino)-1-(3-pyridyl)-1-
butanone (NNK), N′-nitroso nornicotine (NNN), N′-nitroso anabasine (NAB) and N …

Determination of carcinogenic tobacco-specific nitrosamines in mainstream smoke from US-brand and non-US-brand cigarettes from 14 countries

W Wu, L Zhang, RB Jain, DL Ashley… - Nicotine & tobacco …, 2005 - academic.oup.com
Tobacco-specific nitrosamines (TSNAs) comprise one of the major classes of carcinogenic
compounds in mainstream cigarette smoke. As part of collaborative efforts between the …

Tobacco-specific nitrosamines (NNAL, NNN, NAT, and NAB) exposures in the US Population Assessment of Tobacco and Health (PATH) Study Wave 1 (2013–2014)

B Xia, BC Blount, T Guillot, C Brosius… - Nicotine and …, 2021 - academic.oup.com
Introduction The tobacco-specific nitrosamines (TSNAs) are an important group of
carcinogens found in tobacco and tobacco smoke. To describe and characterize the levels …

Metabolism of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone to its biomarker total NNAL in smokeless tobacco users

SS Hecht, SG Carmella, I Stepanov, J Jensen… - … Biomarkers & Prevention, 2008 - AACR
Abstract The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
(NNK) is one of the most abundant carcinogens in smokeless tobacco products. NNK uptake …

Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in smokers in the United States: NHANES 2007–2008

Y Xia, JT Bernert, RB Jain, DL Ashley, JL Pirkle - Biomarkers, 2011 - Taylor & Francis
The tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), a
metabolite of the tobacco-specific nitrosamine (TSNA) 4-(methylnitrosamino)-1-(3-pyridyl)-1 …

Tobacco-specific nitrosamines in tobacco from US brand and non-US brand cigarettes

DL Ashley, MD Beeson, DR Johnson… - Nicotine & tobacco …, 2003 - academic.oup.com
Tobacco-specific nitrosamines (TSNAs) are one of the major classes of carcinogens found in
tobacco products. As part of collaborative efforts to reduce tobacco use and resulting …