The cortical microcircuit is built with recurrent excitatory connections, and it has long been
suggested that the purpose of this design is to enable intrinsically driven reverberating …

Slow-wave sleep consists in slowly recurring waves that are associated with a large-scale
spatio-temporal synchrony across neocortex. These slow-wave complexes alternate with …

Sensory information reaches the cortex via thalamocortical (TC) synapses in layer 4.
Thalamic relay neurons that mediate information flow to cortex operate in two distinct modes …

Normal brain function requires interactions between spatially separated, and functionally
specialized, macroscopic regions, yet the directionality of these interactions in large-scale …

Traveling waves of neural activity are frequently observed to occur in concert with the
presentation of a sensory stimulus or the execution of a movement. Although such waves …

Large-amplitude sleep slow oscillations group faster neuronal oscillations and are of
functional relevance for memory performance. However, relatively little is known about the …

Hippocampal activity is fundamental for episodic memory formation and consolidation.
During phases of rest and sleep, it exhibits sharp-wave/ripple (SPW/R) complexes, which …

The consolidation of memories for places and events is thought to rely, at the network level,
on the replay of spatially tuned neuronal firing patterns representing discrete places and …

Neurons in cerebral cortical circuits interact by sending and receiving electrical impulses
called spikes. The ongoing spiking activity of cortical circuits is fundamental to many …

How do neurons encode and store information for long periods of time? Recurring patterns
of activity have been reported in various cortical structures and were suggested to play a …