Aerosolized antibiotics potentially enable delivery of drugs directly at the site of lung
infection with limited systemic side effects. Progress in understanding determinants of …

The treatment of infection typically involves administration of antibiotics by a systemic route,
such as intravenous or oral. However, pulmonary infections can also be approached by …

Introduction-In theory, using inhaled antibiotics for the treatment of pulmonary infections
should have several advantages over the same compounds presented by more …

Aerosolised antimicrobial agents have been used in clinical practice since the 1950s. The
main advantage of this route of administration is the targeted drug delivery to the site of …

Critically ill patients, who develop ventilator-associated pneumonia during prolonged
mechanical ventilation, often require antimicrobial agents administered through the …

AEROSOLIZED ANTIBIOTICS HAVE been used for morc than 50 years, primarily in the
treatment of cystic fibrosis (CF) lung disease [1, 2]. Many antibiotics, particularly …

Administration of medications via aerosolization is potentially an ideal strategy to treat
airway diseases. This delivery method ensures high concentrations of the medication in the …

Targeted pulmonary drug delivery of antibiotics by inhalation aerosols can play significant
roles in the treatment of cystic fibrosis (CF), chronic obstructive pulmonary disease (COPD) …

Many systemic antibiotics penetrate poorly into respiratory secretions. Inhaled antibiotics
offer the theoretical advantage of high local concentrations at the site of infection, with …

Recent reports and studies reveal an increased interest in the use of aerosolized antibiotics
in many clinical situations. Most of these studies address the use of inhaled …