Patients with more severe symptoms of neuropathic ocular pain report more frequent and severe chronic overlapping pain conditions and psychiatric disease

AM Crane, RC Levitt, ER Felix… - British Journal of …, 2017 - bjo.bmj.com
Objective To study chronic pain and mental health profiles in patients with dry eye (DE)
symptoms, comparing those with high and low levels of neuropathic ocular pain (NOP) …

Relationship between dry eye symptoms and pain sensitivity

J Vehof, D Kozareva, PG Hysi, J Harris… - JAMA …, 2013 - jamanetwork.com
Importance Dry eye disease (DED) is common, but little is known about factors contributing
to symptoms of dry eye, given the poor correlation between these symptoms and objective …

Evidence of central sensitisation in those with dry eye symptoms and neuropathic-like ocular pain complaints: incomplete response to topical anaesthesia and …

AM Crane, W Feuer, ER Felix, RC Levitt… - British Journal of …, 2017 - bjo.bmj.com
Objective To evaluate how closely neuropathic-like ocular pain (NOP) symptoms align with a
metric of central sensitisation (ie, the presence of persistent ocular pain after topical …

Epidemiology of discordance between symptoms and signs of dry eye

ES Ong, ER Felix, RC Levitt, WJ Feuer… - British Journal of …, 2018 - bjo.bmj.com
Background/aims The frequent lack of association between dry eye (DE) symptoms and
signs leads to challenges in diagnosing and assessing the disease. Methods Participants …

The corneal pain system. Part I: the missing piece of the dry eye puzzle

P Rosenthal, D Borsook - The ocular surface, 2012 - Elsevier
The traditional model of dry eye disease based on tear deficiency has presented us with
many unanswered questions. Recent studies support the notion that dry eye-like symptoms …

Modification of the Neuropathic Pain Symptom Inventory for use in eye pain (NPSI-Eye)

M Farhangi, W Feuer, A Galor, D Bouhassira, RC Levitt… - Pain, 2019 - journals.lww.com
Chronic eye pain, which has previously been assumed to be due to ocular surface
abnormalities (ie,“dry eye [DE] disease”), has recently garnered attention as a potential …

Corneal pain without stain: is it real?

P Rosenthal, I Baran, DS Jacobs - The ocular surface, 2009 - Elsevier
Clinicians often encounter patients who report corneal pain suggestive of dry eye disease,
yet lack equivalent signs. These patients represent a diagnostic and therapeutic challenge …

Self-reported assessment of dry eye in a population-based setting.

K Bandeen-Roche, B Muñoz… - … & visual science, 1997 - iovs.arvojournals.org
PURPOSE: To report on a subjective dry eye assessment method for use in large-scale
research, to evaluate its application in a population-based study of dry eye among elderly …

Symptoms of ocular irritation in patients diagnosed with dry eye

KK Nichols, CG Begley, B Caffery… - Optometry and vision …, 1999 - journals.lww.com
Abstract colon; Purpose: The purpose of this study was to develop a pilot survey to evaluate
ocular irritation symptom frequency, severity, and impact on daily activity in patients …

The negative effects of dry eye disease on quality of life and visual function

LW Guo, E Akpek - Turkish journal of medical sciences, 2020 - journals.tubitak.gov.tr
In recent years, dry eye has become a hot topic within ophthalmology and optometry,
especially in regards to new frontiers in treatment modalities which include novel devices …